Protein Alignment aPKC and prkch

DIOPT Version :9

• Sequence 1: NP_001260984.1
• Gene: aPKC / 47594
• FlyBaseID: FBgn0261854
• Length: 958
• Species: Drosophila melanogaster
• Sequence 2: XP_002939521.2
• Gene: prkch / 100151731
• XenbaseID: XB-GENE-486685
• Length: 691
• Species: Xenopus tropicalis
• Alignment Length: 543
• Identity: 220/543 - (40%)
• Similarity: 309/543 - (56%)
• Gaps: 91/543 - (16%)

  Fly   483 RRGARRWRKLYRVNGHIFQAKRFNRRAFCAYCQDRIWGL-GRQGFKCIQCKLLVHKKCHKLVQKH 546
            |:.|.| |::::||||.|.|....:..:|::|:|.|||: |:||::|..|..:|||:||:|:...
 Frog   157 RQRAMR-RRVHQVNGHKFMATYLKQPTYCSHCKDFIWGVFGKQGYQCQVCTCVVHKRCHQLIVTA 220

  Fly   547 CT-DQPEPLVKERAEESSDPIPVP---------LP------------------------------ 571
            || ......|:::..|....|.:|         :|
 Frog   221 CTCKSTTSKVEKQIFEQRFGINLPHKFRYHNYKVPTFCDHCGSLLWGLVKQGLQCKICKMNVHKR 285

  Fly   572 ------------------------------PLPYEAMSGGAEACETHDHAHIVAPPPPEDPL-EP 605
                                          |....::||..::    |..|:     .||.: ..
 Frog   286 CEANVAHNCGVNSVDLANALAGMGLHPGNIPFKQHSVSGSVDS----DSNHL-----EEDSISNT 341

  Fly   606 GTQRQYSLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVFET 670
            .:|.::.::||..:||:|:||:.||::.:.:.:..:||:||:||.::..|:|::...|||.:...
 Frog   342 SSQYKFGIDDFTFLRVLGKGSFGKVMLAKSKESDSLYAVKVLKKDVILQDDDVECTMTEKRILSL 406

  Fly   671 ASNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLHEKG 735
            |.|||||..|..||||..|||||:|||.|||||:|:|:.||..|..|.||:|||:.||.|||:||
 Frog   407 ACNHPFLTQLFCCFQTLDRLFFVMEFVNGGDLMFHIQKSRRFDEARACFYSAEITSALMFLHDKG 471

  Fly   736 IIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWA 800
            :|||||||||||||||||.||.|:||||||||.|.|||||||||:|||||||:...||..|||||
 Frog   472 VIYRDLKLDNVLLDHEGHCKLADFGMCKEGIREGCTTSTFCGTPDYIAPEILQEMQYGPLVDWWA 536

  Fly   801 LGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVLKGFLNKNPAD 865
            :||||||||.|.:||:    :||     ||.||:.||...:..|..||..|..:|:.|:.|.||.
 Frog   537 MGVLLYEMLCGHAPFE----AEN-----EDDLFEAILNDEVVYPGWLSQDAVEILQAFMKKKPAK 592

  Fly   866 RLGCHRESAFMDIVSHPFFKNMDWELLERKQVTPPFKPRLDSDRDLANFPPEFTGEAVQLTPDDD 930
            |||.........|:.|||||:::|:.|.:|.:.|||:||:.:..|::||.|||..|...|||.|:
 Frog   593 RLGSLSLGGEKAILWHPFFKDINWDELNKKTIEPPFRPRIKAREDVSNFDPEFIKEDAVLTPIDE 657

  Fly   931 HVIDNIDQSEFEGFEYVNPLLMS 953
            .::..|:|.||..|.|..|.|.:
 Frog   658 SLLPLINQEEFRNFSYTAPELQN 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_1	498..550	CDD:278556	22/53 (42%)
		S_TKc	616..884	CDD:214567	147/267 (55%)
		STKc_aPKC	620..947	CDD:270740	173/326 (53%)
prkch	XP_002939521.2	C2_PKC_epsilon	7..139	CDD:175981
		C1_1	171..221	CDD:365894	20/49 (41%)
		C1_1	245..295	CDD:365894	1/49 (2%)
		STKc_nPKC_eta	356..678	CDD:270742	175/330 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D222529at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010