Protein Alignment aPKC and prkcq

DIOPT Version :9

• Sequence 1: NP_001260984.1
• Gene: aPKC / 47594
• FlyBaseID: FBgn0261854
• Length: 958
• Species: Drosophila melanogaster
• Sequence 2: XP_012813823.2
• Gene: prkcq / 100038268
• XenbaseID: XB-GENE-487643
• Length: 699
• Species: Xenopus tropicalis
• Alignment Length: 586
• Identity: 209/586 - (35%)
• Similarity: 295/586 - (50%)
• Gaps: 127/586 - (21%)

  Fly   477 EDRSIY-----RRGARRWRKLYRVNGHIFQAKRFNRRAFCAYCQDRIWGLGRQGFKCIQCKLLVH 536
            ||.|.:     ||||.:..|:::|..|.|.|..|.:..||:.|.:.:|||.:||::|.||...:|
 Frog   131 EDDSSHFALHQRRGAMKQAKVHQVKCHEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIH 195

  Fly   537 KKCHKLVQKHCT------------------DQP-------------------------------- 551
            |||...|...||                  |.|
 Frog   196 KKCIDKVIAKCTGSAVNSKETVLHKERFKIDMPHRFKVNNYRSPTFCEHCGTLLWGLARQGLKCA 260

  Fly   552 --------------------------------EPLVKERAEESSDPI----PVPLPP-------- 572
                                            |...::|.:..|:.|    ||.:.|
 Frog   261 ECNMNVHHKCAVKVANLCGVNQKLMAEALAMIETTQQDRRQRDSEFIYREGPVNVGPTTNTQDQP 325

  Fly   573 --LPYEAMSGG------AEACETHDHAHIVAPPPPEDPLEPGT-QRQYSLNDFELIRVIGRGSYA 628
              |..:..|.|      .|:.:..:     :||.||..:|..: |.:.:.:||.|.:::|:||:.
 Frog   326 IVLSIKKESQGISWESPIESIKVQE-----SPPEPELKIEQSSCQIKVTFSDFVLHKMLGKGSFG 385

  Fly   629 KVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVFETASNHPFLVGLHSCFQTPSRLFFV 693
            ||.:.||:||.:.:|:||:||.:|..|:|::....||.|...|..||||..|:..|||...||||
 Frog   386 KVFLAELKRTNQFFAIKVLKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTHLYCTFQTKEHLFFV 450

  Fly   694 IEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLHEKGIIYRDLKLDNVLLDHEGHIKLTD 758
            :|::.|||||:|:|...:.....|.||||||...|.|||.||::||||||||:|||.|||||:.|
 Frog   451 MEYLNGGDLMFHIQSCHKFDLPRATFYAAEIVCGLQFLHSKGVVYRDLKLDNILLDMEGHIKIAD 515

  Fly   759 YGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASEN 823
            :|||||.:.....||||||||:|||||||.|:.|.:|||||:.||||||||.|:|||.  |..
 Frog   516 FGMCKESMLGDAKTSTFCGTPDYIAPEILLGQKYNYSVDWWSFGVLLYEMLIGQSPFH--GID-- 576

  Fly   824 PDQNTEDYLFQVILEKTIRIPRSLSVRAASVLKGFLNKNPADRLGCHRESAFMDIVSHPFFKNMD 888
                 |:.|||.|.......||.||:.|..:|.....:.|..|||...     ||..|.||:::|
 Frog   577 -----EEELFQSIRMDNPMYPRFLSMEAKDILIMLFVREPERRLGVKG-----DIRQHCFFQHID 631

  Fly   889 WELLERKQVTPPFKPRLDSDRDLANFPPEFTGEAVQLTPDDDHVIDNIDQSEFEGFEYVNPLLMS 953
            |..||.:::.|||||::.|..|.:||..||..|..:|:..:..:|:::||:.|..|.:|||.:.:
 Frog   632 WGRLENREIEPPFKPKVKSADDWSNFDKEFLNEKPRLSSSERTLINSMDQNMFNNFSFVNPKMEA 696

  Fly   954 L 954
            :
 Frog   697 I 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_1	498..550	CDD:278556	22/69 (32%)
		S_TKc	616..884	CDD:214567	131/267 (49%)
		STKc_aPKC	620..947	CDD:270740	153/326 (47%)
prkcq	XP_012813823.2	C1_nPKC_theta-like_rpt1	150..210	CDD:410384	24/59 (41%)
		C1_nPKC_theta-like_rpt2	229..278	CDD:410387	0/48 (0%)
		STKc_nPKC_theta	367..697	CDD:270770	159/343 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D222529at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920