Protein Alignment NELL2 and NimC2

DIOPT Version :9

• Sequence 1: XP_016874830.1
• Gene: NELL2 / 4753
• HGNCID: 7751
• Length: 871
• Species: Homo sapiens
• Sequence 2: NP_001285922.1
• Gene: NimC2 / 34818
• FlyBaseID: FBgn0028939
• Length: 701
• Species: Drosophila melanogaster
• Alignment Length: 685
• Identity: 161/685 - (23%)
• Similarity: 220/685 - (32%)
• Gaps: 251/685 - (36%)

Human   284 PTCNDFHGLVQKIMELQDILAKTSAKLSRAEQRMNRLDQCYCERTCTMKGTTYREFESWIDG-C- 346
            |.|||. |...|.: |.::.......:||.       |..:||..|:         ||.::| |
  Fly    79 PLCNDC-GASGKCL-LPNVCLCGKGYVSRK-------DHGHCEPECS---------ESCVNGKCV 125

Human   347 --KNCTCL------NGT-IQCETLI---CPNPDCPLKSALAYVDGKC-C----------KECKSI 388
              ..|.||      ||: ..||.:.   |.|..| |::      ||| |          |:|..|
  Fly   126 APDECECLAGHRFVNGSQTACEPICVEDCANGRC-LET------GKCLCNNGYQRDEKLKKCVPI 183

Human   389 CQ---FQGRTYFEGE-------------------------RNTVYSSSGVCVL---YECKDQTMK 422
            ||   :.|......|                         .|.....:.||..   |..||.|:
  Fly   184 CQDACYHGDCVAPNECRCHPGHEQRLGVPWICDPICSSGCANGYCQGAEVCACKMGYAHKDNTL- 247

Human   423 LVESSGC-PALDCPESHQITLSHSCCKVCKGYDFC-SERHNCMENSICRNLNDRAVCSCRDGFRA 485
               :||| |..:.|.::...:|...|...:|:.|. ..||.|             |.|||.|.
  Fly   248 ---ASGCEPVCNPPCTNGTCISPGHCACSEGHVFAEGSRHEC-------------VPSCRSGC-- 294

Human   486 LREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDE 550
               :|.||                    ::||  .|.|..|:.:...:.|:.     |.:..|.:
  Fly   295 ---ENGYC--------------------SSPG--RCECHEGFEKTSPHRCSP-----TCRPGCGQ 329

Human   551 NALCFNTVGGHNCVCKPGY---TGNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDID 612
            |:.|   .....|.|..||   .|:.|.|:.||...||| |.|.:..||.|.:||........|.
  Fly   330 NSRC---AAPDTCACDVGYVFVNGSTTECEPFCPRNCRN-GICSSPGVCTCLEGFQALLSFYCIP 390

Human   613 ECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPS--GESCEDIDECGTGRHSCANDTICF 675
            .||...:    ..:|: .|.  .|.|..||..|    ||  ...||.|...|.....|....||
  Fly   391 VCSKTCI----HGSCV-APN--ECRCFTGYRPN----PSLGANVCEPICSQGCVHGFCIAPEIC- 443

Human   676 NLDGGYDCR-----C-PHGKNCTGDCIHDGKVKHNGQIWVLENDRC---SVCSCQNGFVMCRRMV 731
            ..|.|:..|     | ||   |...|:               |..|   .||.|..|:.:
  Fly   444 QCDLGFIKRWATGTCEPH---CPQKCV---------------NSHCLGSGVCRCYEGYKL----- 485

Human   732 CDCENPTVDLFCCPECDPRL-SSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVDCWPLPCPDVE 795
                .|.....|.|||.|.. :..|:..|                .|.|..|        ..|.:
  Fly   486 ----RPGSTSICDPECQPGCRNGTCVEPN----------------SCACFAG--------YEDTK 522

Human   796 CEFSILPENECCPRC------------------VTDPCQADTIRNDITKTCLDEMNVV------- 835
            ..:..:|  .|.|||                  ||:..:.::.|....:.|::...|.
  Fly   523 VPYECVP--SCRPRCENGRCSSPGHCECDPGHVVTNSSEPNSCRPQCQEQCINAECVAPEKCACL 585

Human   836 ---RFTGSSWIKHGTEC-TLCQ--CKNGHICCSVD 864
               ||...|    .||| .:|.  |.:|..|.:.|
  Fly   586 PRYRFLPDS----STECEPICSKGCLSGQECVAPD 616

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910