| Sequence 1: | NP_006149.2 | Gene: | NEFL / 4747 | HGNCID: | 7739 | Length: | 543 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001260974.1 | Gene: | LamC / 36615 | FlyBaseID: | FBgn0010397 | Length: | 640 | Species: | Drosophila melanogaster |
| Alignment Length: | 559 | Identity: | 149/559 - (26%) |
|---|---|---|---|
| Similarity: | 237/559 - (42%) | Gaps: | 113/559 - (20%) |
- Green bases have known domain annotations that are detailed below.
|
Human 28 SVRSGYSTARSAYSSYSAPVSSSLSVRRSYSSSSGSLMPSLENLDLSQVAAISNDLKSIRTQEKA 92
Human 93 QLQDLNDRFASFIERVHELEQQNKVLEAEL-LVLRQKHSEPSRFRALYEQEIRDLRLAAEDATNE 156
Human 157 KQALQ-------GEREGL--------------EETLRNLQARY---------------------E 179
Human 180 EEVLSREDAEGRLMEARKGADEAALARAELEKRIDSLMDEISFLKKVHEEEIAELQA--QIQYAQ 242
Human 243 ISVEMD-VTKPDLSAALKDIRAQYEKLAAKNMQNAEEWFKSRFTVLTESAAKNTDAVRAAKDEVS 306
Human 307 ESRRLLKAKTLEIEACRGMNEALEKQLQELEDKQNADISAMQDTINKLENELRTTKSEMARYLKE 371
Human 372 YQDLLNVKMALDIEIAAYRKLLEGEETRLSFTSVGSIT--------------SGYSQSSQVF--- 419
Human 420 GRSAYGGLQTSSYLMSTRSFPSYYTSHVQEEQIEVEETIEAAKAEEAKDEPPSEGEAEEEEKDKE 484
Human 485 --------EAEEE---------EAAEEEEAAKEESEEAK 506 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| NEFL | NP_006149.2 | Head | 2..92 | 15/63 (24%) | |
| Filament_head | 9..88 | CDD:309741 | 12/59 (20%) | ||
| Filament | 89..399 | CDD:306535 | 103/355 (29%) | ||
| Coil 1A | 93..124 | 15/31 (48%) | |||
| Linker 1 | 125..137 | 2/11 (18%) | |||
| Coil 1B | 138..234 | 31/137 (23%) | |||
| Linker 12 | 235..252 | 3/19 (16%) | |||
| Coil 2A | 253..271 | 6/17 (35%) | |||
| Linker 2 | 272..280 | 2/7 (29%) | |||
| Coil 2B | 281..396 | 35/114 (31%) | |||
| Epitope, recognized by IF-specific monoclonal antibody | 381..391 | 7/9 (78%) | |||
| Tail | 397..543 | 34/144 (24%) | |||
| Tail, subdomain A | 397..443 | 17/62 (27%) | |||
| Tail, subdomain B (acidic) | 444..543 | 17/80 (21%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 462..543 | 13/62 (21%) | |||
| LamC | NP_001260974.1 | Filament | 45..401 | CDD:278467 | 103/355 (29%) |
| ATP-synt_B | <67..>142 | CDD:304375 | 19/74 (26%) | ||
| MreC | <178..>224 | CDD:302802 | 15/45 (33%) | ||
| LTD | 473..574 | CDD:279300 | 15/65 (23%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.910 | |||||