| Sequence 1: | NP_006149.2 | Gene: | NEFL / 4747 | HGNCID: | 7739 | Length: | 543 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001245892.1 | Gene: | Lam / 33782 | FlyBaseID: | FBgn0002525 | Length: | 622 | Species: | Drosophila melanogaster |
| Alignment Length: | 509 | Identity: | 142/509 - (27%) |
|---|---|---|---|
| Similarity: | 234/509 - (45%) | Gaps: | 88/509 - (17%) |
- Green bases have known domain annotations that are detailed below.
|
Human 35 TARSAYSSYSAPVSSSLSVRRSYSSSSGSLMPSLENLDLSQVAAIS-NDLKSIRTQEKAQLQDLN 98
Human 99 DRFASFIERVHELEQQN----------------------KVLEAELLVLRQKHSEPSRFRALYEQ 141
Human 142 EIR-------DLRLAAEDATNEKQALQGEREGLEETLRNLQARYEEEVLSREDAEGRLMEA---- 195
Human 196 ----------RKGADEAALARAELEKRIDSLMDEISFLKKVHEEEIAELQ--AQIQYAQI----S 244
Human 245 VEMDVTKPDLSAALKDIRAQYEKLAAKNMQNAEEWFKSRFTVLTESAAKNTDAVRAAKDEVSESR 309
Human 310 RLLKAKTLEIEACRGMNEALEKQLQELEDKQNADISAMQDTINKLENELRTTKSEMARYLKEYQD 374
Human 375 LLNVKMALDIEIAAYRKLLEGEETRLSFTSVGSITS--GYSQSSQVFGRSAYGGLQTSSYLMSTR 437
Human 438 SFPSYYT--SHVQEEQIEVEETIEAAKAE-----EAKDEPPSEGEAEEEEKDKE 484 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| NEFL | NP_006149.2 | Head | 2..92 | 12/57 (21%) | |
| Filament_head | 9..88 | CDD:309741 | 10/53 (19%) | ||
| Filament | 89..399 | CDD:306535 | 108/358 (30%) | ||
| Coil 1A | 93..124 | 17/52 (33%) | |||
| Linker 1 | 125..137 | 2/11 (18%) | |||
| Coil 1B | 138..234 | 28/116 (24%) | |||
| Linker 12 | 235..252 | 6/22 (27%) | |||
| Coil 2A | 253..271 | 7/17 (41%) | |||
| Linker 2 | 272..280 | 1/7 (14%) | |||
| Coil 2B | 281..396 | 38/114 (33%) | |||
| Epitope, recognized by IF-specific monoclonal antibody | 381..391 | 7/9 (78%) | |||
| Tail | 397..543 | 24/97 (25%) | |||
| Tail, subdomain A | 397..443 | 12/47 (26%) | |||
| Tail, subdomain B (acidic) | 444..543 | 12/48 (25%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 462..543 | 8/28 (29%) | |||
| Lam | NP_001245892.1 | Filament | 54..409 | CDD:278467 | 108/357 (30%) |
| Ax_dynein_light | <283..377 | CDD:287215 | 20/93 (22%) | ||
| LTD | 466..572 | CDD:279300 | 7/22 (32%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.910 | |||||