DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ytr and SNRNP27

DIOPT Version :9

Sequence 1:	NP_001286785.1	Gene:	ytr / 47457	FlyBaseID:	FBgn0021895	Length:	194	Species:	Drosophila melanogaster
Sequence 2:	NP_006848.1	Gene:	SNRNP27 / 11017	HGNCID:	30240	Length:	155	Species:	Homo sapiens

Alignment Length:	203	Identity:	88/203 - (43%)
Similarity:	109/203 - (53%)	Gaps:	57/203 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGRSRSPASPAHRRREKERSERKKRRERRSREREAIGVAPAGGSGSGGAGRRDRERDRDRSRSRD 65
            ||||||            ||.|::||..||..||                   ||| |.|.|||.
Human     1 MGRSRS------------RSPRRERRRSRSTSRE-------------------RER-RRRERSRS 33

  Fly    66 RERERERDRARS---RRSRSRSRVAGGGGGGGGGGSSGGNSSSGPSTSRRTTRNN-----AAATA 122
            |||:|.|.|:||   |||||..|                :.|:.||.||...|.:     ...|.
Human    34 RERDRRRSRSRSPHRRRSRSPRR----------------HRSTSPSPSRLKERRDEEKKETKETK 82

  Fly   123 ADRPKINEADLEGKSPEEVEMLKTMGFCTFDTTKNRKVEGN-DVGEVHVILKRKYRQYMNRKGGF 186
            :...:|.|.|||||:.||:||:|.|||.:||:||.:||:|: :...::|..||||||||||||||
Human    83 SKERQITEEDLEGKTEEEIEMMKLMGFASFDSTKGKKVDGSVNAYAINVSQKRKYRQYMNRKGGF 147

  Fly   187 NRPLDFVA 194
            ||||||:|
Human   148 NRPLDFIA 155

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ytr	NP_001286785.1	DUF1777	<124..190	CDD:285811	39/66 (59%)
SNRNP27	NP_006848.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..97		50/143 (35%)
SNRNP27	NP_006848.1	DUF1777	98..154	CDD:400810	35/55 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	78	1.000	Domainoid score	I8838
eggNOG	1	0.900	-	-		E1_KOG3263
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	127	1.000	Inparanoid score	I4695
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1627375at2759
OrthoFinder	1	1.000	-	-		FOG0006213
OrthoInspector	1	1.000	-	-		oto90444
orthoMCL	1	0.900	-	-		OOG6_103584
Panther	1	1.100	-	-	LDO	PTHR31077
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1369
SonicParanoid	1	1.000	-	-		X4489
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.860