DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2AB1 and His2A:CG33832

DIOPT Version :9

Sequence 1:	NP_001017990.1	Gene:	H2AB1 / 474382	HGNCID:	22516	Length:	115	Species:	Homo sapiens
Sequence 2:	NP_001027331.1	Gene:	His2A:CG33832 / 3772632	FlyBaseID:	FBgn0053832	Length:	124	Species:	Drosophila melanogaster

Alignment Length:	100	Identity:	47/100 - (47%)
Similarity:	67/100 - (67%)	Gaps:	2/100 - (2%)

- Green bases have known domain annotations that are detailed below.

Human    12 GAGG--RGRTCSRTVRAELSFSVSQVERSLREGHYAQRLSRTAPVYLAAVIEYLTAKVPELAGNE 74
            |.||  :|:..||:.||.|.|.|.::.|.||:|:||:|:...||||||||:|||.|:|.|||||.
  Fly     5 GKGGKVKGKAKSRSNRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLELAGNA 69

Human    75 AQNSGERNITPLLLDMVVHNDRLLSTLFNTTTISQ 109
            |:::.:..|.|..|.:.:.||..|:.|.:..||:|
  Fly    70 ARDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQ 104

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2AB1	NP_001017990.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21		4/10 (40%)
		H2A	21..113	CDD:197711	42/88 (48%)
		H2A	21..112	CDD:305064	42/88 (48%)
		Docking domain. /evidence=ECO:0000269\|PubMed:15257289	87..115		7/22 (32%)
His2A:CG33832	NP_001027331.1	PTZ00017	16..124	CDD:185399	42/88 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5262
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810