DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vps28 and vps28

DIOPT Version :9

Sequence 1:	NP_001260796.1	Gene:	Vps28 / 47408	FlyBaseID:	FBgn0021814	Length:	210	Species:	Drosophila melanogaster
Sequence 2:	XP_012810557.1	Gene:	vps28 / 549068	XenbaseID:	XB-GENE-5776981	Length:	247	Species:	Xenopus tropicalis

Alignment Length:	204	Identity:	135/204 - (66%)
Similarity:	171/204 - (83%)	Gaps:	0/204 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 PELYEEVKLFRNAREREKYDNMADLYAIINTIQQLEKAYIRDCITPQEYTAACSKYLVQYKVAFK 70
            |||||||||::||||||||||||:|:|::.|:|.||||||:||::|.|||||||:.|||||.|||
Frog    44 PELYEEVKLYKNAREREKYDNMAELFAVVKTLQALEKAYIKDCVSPSEYTAACSRLLVQYKAAFK 108

  Fly    71 QVQCDEFPSVETFVKKFRLDCPAALERIREDRPITIRDDKGNTSKCIAEIVSLFITIMDKLRLQI 135
            |||..|..|::.|.:|:|||||.|:|||:|||||||:|||||.::|||:|||||||:||||||:|
Frog   109 QVQGAEVGSIDDFCRKYRLDCPLAMERIKEDRPITIKDDKGNLNRCIADIVSLFITVMDKLRLEI 173

  Fly   136 NTMDALQPDVKDLADNMNRLSLIPEDFDAKLKVEKWLGSLNEMQASDELSEGQVRQFLFDLESAY 200
            ..||.:|||:::|.:.|||:|.:|.||:.:.||.:||..|:.|.|||||.:.||||.||||||||
Frog   174 RAMDEIQPDLRELMETMNRMSHLPPDFEGREKVSQWLQKLSSMSASDELDDSQVRQMLFDLESAY 238

  Fly   201 ADFNKLLHS 209
            ..||:.|||
Frog   239 NAFNRFLHS 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vps28	NP_001260796.1	VPS28	27..207	CDD:397894	113/179 (63%)
vps28	XP_012810557.1	VPS28	65..245	CDD:281926	113/179 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	247	1.000	Domainoid score	I2119
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H69205
Inparanoid	1	1.050	292	1.000	Inparanoid score	I2733
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1281819at2759
OrthoFinder	1	1.000	-	-		FOG0004132
OrthoInspector	1	1.000	-	-		oto105394
Panther	1	1.100	-	-	LDO	PTHR12937
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2885
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160