DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vps28 and vps28

DIOPT Version :9

Sequence 1:	NP_001260796.1	Gene:	Vps28 / 47408	FlyBaseID:	FBgn0021814	Length:	210	Species:	Drosophila melanogaster
Sequence 2:	NP_956884.1	Gene:	vps28 / 393562	ZFINID:	ZDB-GENE-040426-1527	Length:	223	Species:	Danio rerio

Alignment Length:	204	Identity:	135/204 - (66%)
Similarity:	170/204 - (83%)	Gaps:	0/204 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 PELYEEVKLFRNAREREKYDNMADLYAIINTIQQLEKAYIRDCITPQEYTAACSKYLVQYKVAFK 70
            |||||||||::||||||||||||:|:|::.|:|.||||||:||:||.|||.|||:.|||||.|||
Zfish    19 PELYEEVKLYKNAREREKYDNMAELFAVVKTLQALEKAYIKDCVTPNEYTGACSRLLVQYKAAFK 83

  Fly    71 QVQCDEFPSVETFVKKFRLDCPAALERIREDRPITIRDDKGNTSKCIAEIVSLFITIMDKLRLQI 135
            |||..:..|::.|.:|:|||||.|:|||:|||||||:|||||.::|||:|||||||:||||||:|
Zfish    84 QVQGSDVGSIDDFCRKYRLDCPLAMERIKEDRPITIKDDKGNLNRCIADIVSLFITVMDKLRLEI 148

  Fly   136 NTMDALQPDVKDLADNMNRLSLIPEDFDAKLKVEKWLGSLNEMQASDELSEGQVRQFLFDLESAY 200
            ..||.:|||:::|.:.|||:|.:|.|.:||.||..||.:|:.|.|||||.:.||||.||||||||
Zfish   149 RAMDEIQPDLRELMETMNRMSNMPPDSEAKDKVSLWLTTLSSMSASDELDDSQVRQMLFDLESAY 213

  Fly   201 ADFNKLLHS 209
            ..||:.|||
Zfish   214 NAFNRFLHS 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vps28	NP_001260796.1	VPS28	27..207	CDD:397894	113/179 (63%)
vps28	NP_956884.1	VPS28	40..220	CDD:281926	113/179 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596576
Domainoid	1	1.000	245	1.000	Domainoid score	I2148
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H69205
Inparanoid	1	1.050	290	1.000	Inparanoid score	I2792
OMA	1	1.010	-	-		QHG53660
OrthoDB	1	1.010	-	-		D1281819at2759
OrthoFinder	1	1.000	-	-		FOG0004132
OrthoInspector	1	1.000	-	-		oto38636
orthoMCL	1	0.900	-	-		OOG6_103220
Panther	1	1.100	-	-	LDO	PTHR12937
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1648
SonicParanoid	1	1.000	-	-		X2885
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	15	14.940