DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vps28 and vps-28

DIOPT Version :9

Sequence 1:	NP_001260796.1	Gene:	Vps28 / 47408	FlyBaseID:	FBgn0021814	Length:	210	Species:	Drosophila melanogaster
Sequence 2:	NP_493382.1	Gene:	vps-28 / 173229	WormBaseID:	WBGene00013598	Length:	210	Species:	Caenorhabditis elegans

Alignment Length:	208	Identity:	97/208 - (46%)
Similarity:	134/208 - (64%)	Gaps:	2/208 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQEQSPELYEEVKLFRNAREREKYDNMADLYAIINTIQQLEKAYIRDCITPQEYTAACSKYLVQY 65
            |..|:..|..||:||.|..|||:.:|:::|:|::|.::.|||.:.||.::..||.:.|.|.:.||
Worm     1 MSSQNANLMREVRLFENHSEREQMENLSELFAVLNALEHLEKMFSRDHVSADEYKSECFKLIDQY 65

  Fly    66 KVAFKQVQCDEFPSVETFVKKFRLDCPAALERIREDRPITIRDDKGNTSKCIAEIVSLFITIMDK 130
            ||..:.|.  ...|:|.|.||:||.||||:|||||.||||::||:||..|.||.||..|||.:|.
Worm    66 KVTMRLVH--GATSIEDFAKKYRLHCPAAIERIREGRPITVKDDQGNVLKHIASIVEQFITFLDA 128

  Fly   131 LRLQINTMDALQPDVKDLADNMNRLSLIPEDFDAKLKVEKWLGSLNEMQASDELSEGQVRQFLFD 195
            |||....:|.|.|.:.||.:.:|..|.:|.|.....||:||...|:.|.||||:|:...||.:||
Worm   129 LRLNTRAVDDLYPGLDDLYNAINTTSRVPIDAIVTTKVKKWHDRLSSMAASDEISDEDARQMIFD 193

  Fly   196 LESAYADFNKLLH 208
            :||||..|||.|:
Worm   194 VESAYQAFNKALN 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vps28	NP_001260796.1	VPS28	27..207	CDD:397894	84/179 (47%)
vps-28	NP_493382.1	VPS28	27..205	CDD:281926	84/179 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167701
Domainoid	1	1.000	167	1.000	Domainoid score	I2344
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H69205
Inparanoid	1	1.050	189	1.000	Inparanoid score	I2569
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53660
OrthoDB	1	1.010	-	-		D1281819at2759
OrthoFinder	1	1.000	-	-		FOG0004132
OrthoInspector	1	1.000	-	-		oto17326
orthoMCL	1	0.900	-	-		OOG6_103220
Panther	1	1.100	-	-	LDO	PTHR12937
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1648
SonicParanoid	1	1.000	-	-		X2885
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.940