Protein Alignment ATOH1 and Fer3

DIOPT Version :9

• Sequence 1: NP_005163.1
• Gene: ATOH1 / 474
• HGNCID: 797
• Length: 354
• Species: Homo sapiens
• Sequence 2: NP_524322.1
• Gene: Fer3 / 41411
• FlyBaseID: FBgn0037937
• Length: 195
• Species: Drosophila melanogaster
• Alignment Length: 253
• Identity: 76/253 - (30%)
• Similarity: 101/253 - (39%)
• Gaps: 99/253 - (39%)

Human    20 HRQP--QPHHLP----QP------PPPPQPPATLQAREHPVYPPELSLLDSTDPRAWLAPTLQGI 72
            |..|  ||.::|    ||      ||||..|          |...::....||...|
  Fly     3 HPHPIDQPTYMPDVPFQPLWGQEAPPPPIVP----------YQELIAGFPCTDLSLW-------- 49

Human    73 CTARAAQYLLHSPELGASEAAAPRDEVDGRGELVRRSSGGASSSKSPGPVKVREQLCKLKGGVVV 137
               :.:|.....|:         |...:|      |::|.:||||.
  Fly    50 ---QRSQVTPLVPQ---------RPSTNG------RANGSSSSSKK------------------- 77

Human   138 DELGCSRQRAPSSKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQ 202
                 :|:|..|..|        |.|||.||||||..||.|||:||..:|:|..:|:||:.|||:
  Fly    78 -----TRRRVASMAQ--------RRAANIRERRRMFNLNEAFDKLRRKVPTFAYEKRLSRIETLR 129

Human   203 MAQIYINALSELLQ-TPS-------------GGEQPPPPPASCKSDH-HHLRTAASYE 245
            :|..||..::|||. |||             .|....||||.    | |||..||:|:
  Fly   130 LAITYIGFMAELLSGTPSNSHKSRSDVYGSMNGHHQAPPPAI----HPHHLHPAAAYQ 183

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATOH1	NP_005163.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55		13/46 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..122		8/30 (27%)
		HLH	158..216	CDD:238036	30/57 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	216..277		15/45 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	312..354
Fer3	NP_524322.1	HLH	87..135	CDD:278439	27/55 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	2.870