Protein Alignment ATOH1 and dimm

DIOPT Version :10

• Sequence 1: NP_005163.1
• Gene: ATOH1 / 474
• HGNCID: 797
• Length: 354
• Species: Homo sapiens
• Sequence 2: NP_523611.1
• Gene: dimm / 35404
• FlyBaseID: FBgn0023091
• Length: 390
• Species: Drosophila melanogaster
• Alignment Length: 311
• Identity: 77/311 - (24%)
• Similarity: 120/311 - (38%)
• Gaps: 72/311 - (23%)

Human    74 TARAAQYLLHSPELGASEAAAPRDEVDGRGELVRRSSGGASSSKSPGPVKVREQLCKL------- 131
            |.|.:|...::.:|..:::::..|:..|.|   ..|:||.|::.:..|     ..|.|
  Fly    53 TRRTSQLSNNTYDLEMTDSSSQSDDTSGGG---GSSNGGGSTTNTGHP-----SGCSLGGQGPSG 109

Human   132 KGGVVVDELG-CSRQRAPSSKQVNG------------------VQKQRRLAANARERRRMHGLNH 177
            :|.|.....| |....||:|...|.                  .:..|||.:|.|||.|||.||.
  Fly   110 RGRVQQASSGACPSTIAPNSTSSNSSNANGNASRRRKGALNAKERNMRRLESNERERMRMHSLND 174

Human   178 AFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQTPSGGEQPPPPPASCKSDHHHLRTAA 242
            ||..||.|||....:::|||.|||.:|:.||..|:.::.:....|                  ||
  Fly   175 AFQSLREVIPHVEMERRLSKIETLTLAKNYIINLTHIILSKRNEE------------------AA 221

Human   243 SYE---GGAGNATAAGAQQASGG---SQRPTPPGSCRTRFSAPASAGGYSVQLDALHFSTFEDSA 301
            :.|   |..|....:.....|||   |..|....:....|....::||   ..|....:..:.|.
  Fly   222 ALELNSGAVGGVLLSNLSSESGGPVASGIPANSNAATICFEDTLASGG---AFDCAILAATDGSL 283

Human   302 LTAMMAQKNLSPSLPG------SILQPVQEENSKTSPRSHRSDGEFSPHSH 346
            |.|  |....||::..      .:..|::::..:.|...|...   :.|.|
  Fly   284 LNA--ATVTTSPAMQSIQSQAIHLQTPMEQQQQQASHLPHHQQ---AMHGH 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATOH1	NP_005163.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..122		7/30 (23%)
		bHLH_TS_ATOH1	155..218	CDD:381556	29/80 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	216..277		11/66 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	312..354		7/41 (17%)
dimm	NP_523611.1	bHLH_TS_dimmed_like	157..216	CDD:381555	29/58 (50%)