Protein Alignment DRG1 and 128up

DIOPT Version :9

• Sequence 1: NP_004138.1
• Gene: DRG1 / 4733
• HGNCID: 3029
• Length: 367
• Species: Homo sapiens
• Sequence 2: NP_536733.1
• Gene: 128up / 36288
• FlyBaseID: FBgn0010339
• Length: 368
• Species: Drosophila melanogaster
• Alignment Length: 367
• Identity: 297/367 - (80%)
• Similarity: 334/367 - (91%)
• Gaps: 0/367 - (0%)

Human     1 MSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDA 65
            ||:.|.||:.||:|||||||||||:.|||||||:|||||||||:|||||||....||:|||||||
  Fly     1 MSTILEKISAIESEMARTQKNKATSAHLGLLKAKLAKLRRELISPKGGGGGTGEAGFEVAKTGDA 65

Human    66 RIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDGKG 130
            |:|||||||||||||||||||||||||||||||||||||.|:|||||||||||||||||||||||
  Fly    66 RVGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGCIKYKGAKIQLLDLPGIIEGAKDGKG 130

Human   131 RGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIGFKKKDKGGINLTATC 195
            |||||||||||||||.:|||.||||||||::|:||||||||||.|||||.:|:||||||||.:..
  Fly   131 RGRQVIAVARTCNLIFMVLDCLKPLGHKKLLEHELEGFGIRLNKKPPNIYYKRKDKGGINLNSMV 195

Human   196 PQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIYVLNKIDQISIEELDI 260
            ||||||.:.||:||:||||||||:|||.|||:||||||:||||:||||||:|||||||||||||:
  Fly   196 PQSELDTDLVKTILSEYKIHNADITLRYDATSDDLIDVIEGNRIYIPCIYLLNKIDQISIEELDV 260

Human   261 IYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYSRTTVEDFCMKI 325
            |||:||||||||||.||||||||.:|:||:|.|||||||||||||.|||||...||::||||.|:
  Fly   261 IYKIPHCVPISAHHHWNFDDLLELMWEYLRLQRIYTKPKGQLPDYNSPVVLHNERTSIEDFCNKL 325

Human   326 HKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDEDVIQIVKK 367
            |:::.||||||||||.||||.|||||.:|.|.||||:|||||
  Fly   326 HRSIAKEFKYALVWGSSVKHQPQKVGIEHVLNDEDVVQIVKK 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DRG1	NP_004138.1	Rbg1	1..367	CDD:224085	295/365 (81%)
		Required for interaction with STK16. /evidence=ECO:0000269|PubMed:18184589	2..16		7/13 (54%)
128up	NP_536733.1	Rbg1	1..367	CDD:224085	295/365 (81%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151438
Domainoid	1	1.000	189	1.000	Domainoid score	I3302
eggNOG	1	0.900	-	-		E1_COG1163
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3060
Inparanoid	1	1.050	616	1.000	Inparanoid score	I904
Isobase	1	0.950	-	0	Normalized mean entropy	S98
OMA	1	1.010	-	-		QHG60797
OrthoDB	1	1.010	-	-		D348788at33208
OrthoFinder	1	1.000	-	-		FOG0001080
OrthoInspector	1	1.000	-	-		oto90118
orthoMCL	1	0.900	-	-		OOG6_102018
Panther	1	1.100	-	-	LDO	PTHR43127
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1835
SonicParanoid	1	1.000	-	-		X3699
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750