DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment repo and shox

DIOPT Version :9

Sequence 1:	NP_477026.1	Gene:	repo / 47285	FlyBaseID:	FBgn0011701	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	XP_005167911.1	Gene:	shox / 664748	ZFINID:	ZDB-GENE-051030-21	Length:	304	Species:	Danio rerio

Alignment Length:	156	Identity:	60/156 - (38%)
Similarity:	81/156 - (51%)	Gaps:	15/156 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   287 KKDGSSSKKKGDPNGIKKKKTRTTFTAYQLEELERAFERAPYPDVFAREELAIKLNLSESRVQVW 351
            ||:...|:.:...:.:|::::||.||..||.||||.|:...|||.|.||||:.:|.|||:|||||
Zfish    92 KKEDVKSEDEDAQSKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVW 156

  Fly   352 FQNRRAKWRKHEPPRKTGYI-KTSTPPTAT-----LNPGTLAPPFTSYPQTTTVTPPGS-----M 405
            |||||||.||.|.....|.| .|::...|.     :|.|.|..||........:...|:     :
Zfish   157 FQNRRAKCRKQENQMHKGVILGTASHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVGTHSHPHL 221

  Fly   406 DSWTSYQTPYEL--TPQFSLLSPAAS 429
            ....:...||.:  .|.|.|  |.||
Zfish   222 HPHLAAHAPYLMFPPPPFGL--PIAS 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
repo	NP_477026.1	Homeobox	313..360	CDD:278475	31/46 (67%)
shox	XP_005167911.1	Homeobox	112..165	CDD:278475	35/52 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.940