Protein Alignment repo and SHOX

DIOPT Version :10

• Sequence 1: NP_477026.1
• Gene: repo / 47285
• FlyBaseID: FBgn0011701
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_000442.1
• Gene: SHOX / 6473
• HGNCID: 10853
• Length: 292
• Species: Homo sapiens
• Alignment Length: 191
• Identity: 70/191 - (36%)
• Similarity: 95/191 - (49%)
• Gaps: 17/191 - (8%)

  Fly   216 NGGSAGGKLKKPDEMCSQ--LEAGGAGVTPPSSSSTVVNGTTNGTGNAN--------SSSSAGVG 270
            |||..||..|| |.:..:  ||:|.|......:|.:.:...|.|.|:..        .:....:.
Human    20 NGGGGGGGGKK-DSITYREVLESGLARSRELGTSDSSLQDITEGGGHCPVHLFKDHVDNDKEKLK 83

  Fly   271 IQGAAGTAGGVAAPAAKKDGSSSKKKGDPNGIKKKKTRTTFTAYQLEELERAFERAPYPDVFARE 335
            ..|.|..|.|:.....|::...|:.:.....:|::::||.||..||.||||.|:...|||.|.||
Human    84 EFGTARVAEGIYECKEKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMRE 148

  Fly   336 ELAIKLNLSESRVQVWFQNRRAKWRKHEPPRKTGYI-KTSTPPTAT-----LNPGTLAPPF 390
            ||:.:|.|||:||||||||||||.||.|.....|.| .|:....|.     :|.|.|..||
Human   149 ELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTANHLDACRVAPYVNMGALRMPF 209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
repo	NP_477026.1	Homeodomain	313..361	CDD:459649	31/47 (66%)
SHOX	NP_000442.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34		8/14 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	100..119		3/18 (17%)
		Homeodomain	118..174	CDD:459649	35/55 (64%)
		SH3-binding. /evidence=ECO:0000255	242..249
		OAR	272..288	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	274..287