DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment repo and alx1

DIOPT Version :9

Sequence 1:	NP_477026.1	Gene:	repo / 47285	FlyBaseID:	FBgn0011701	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_001038539.1	Gene:	alx1 / 565176	ZFINID:	ZDB-GENE-050419-191	Length:	320	Species:	Danio rerio

Alignment Length:	196	Identity:	71/196 - (36%)
Similarity:	97/196 - (49%)	Gaps:	47/196 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   283 APAA----KKDGSSSKKKGDPN--GIKKKKTRTTFTAYQLEELERAFERAPYPDVFAREELAIKL 341
            :||.    |.|.....:|.|.|  ..||::.|||||:.||||||:.|::..||||:.||:||::.
Zfish    93 SPATSGPDKTDLDELGEKCDSNVSSSKKRRHRTTFTSAQLEELEKVFQKTHYPDVYVREQLAMRT 157

  Fly   342 NLSESRVQVWFQNRRAKWRKHEPPRKTGYIKTSTPPTATLNPGTLAPPFTSYPQ----------- 395
            .|:|:|||||||||||||||.|   :.|.|:.:....|.....::.|...||.|
Zfish   158 ELTEARVQVWFQNRRAKWRKRE---RYGQIQQAKSHFAATYDISMLPRTDSYSQISNNLWTGPSA 219

  Fly   396 -----TTTVTPPGSMDSWTSYQTPYELTPQFSLLSPAASPYGTYSGQYGAYV----HESQLFPMR 451
                 ::.:.|.||....||   ||   |.    ||.|:.:|        ||    |:...|.:.
Zfish   220 GSSVVSSCMIPRGSPPCVTS---PY---PH----SPRAAEHG--------YVGFPNHQQNQFGVN 266

  Fly   452 H 452
            |
Zfish   267 H 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
repo	NP_477026.1	Homeobox	313..360	CDD:278475	29/46 (63%)
alx1	NP_001038539.1	Homeobox	123..176	CDD:278475	34/52 (65%)
		Transactivation domain. /evidence=ECO:0000250\|UniProtKB:Q63087	180..320		24/106 (23%)
		OAR	296..313	CDD:281777
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	300..313
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24329
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010