DRSC/TRiP Functional Genomics Resources

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Protein Alignment repo and DUXA

DIOPT Version :10

Sequence 1:NP_477026.1 Gene:repo / 47285 FlyBaseID:FBgn0011701 Length:612 Species:Drosophila melanogaster
Sequence 2:NP_001012747.1 Gene:DUXA / 503835 HGNCID:32179 Length:204 Species:Homo sapiens


Alignment Length:89 Identity:38/89 - (42%)
Similarity:56/89 - (62%) Gaps:8/89 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly   284 PAAKKDGSSSKKKGDPNGI-----KKKKTRTTFTAYQLEELERAFERAPYPDVFAREELAIKLNL 343
            |.|:...||..:..|..|:     :.::.|||::|.||..|.:||.:.|||.:.:|||||.::.:
Human    76 PEAETLESSQSQGQDQPGVEFQSREARRCRTTYSASQLHTLIKAFMKNPYPGIDSREELAKEIGV 140

  Fly   344 SESRVQVWFQNRRAK---WRKHEP 364
            .|||||:||||||::   .||.||
Human   141 PESRVQIWFQNRRSRLLLQRKREP 164

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
repoNP_477026.1 Homeodomain 313..361 CDD:459649 25/50 (50%)
DUXANP_001012747.1 homeodomain 16..74 CDD:238039
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 73..101 6/24 (25%)
Homeodomain 102..155 CDD:459649 28/52 (54%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 163..204 2/2 (100%)
Blue background indicates that the domain is not in the aligned region.

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