DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment repo and lhx6a

DIOPT Version :9

Sequence 1:	NP_477026.1	Gene:	repo / 47285	FlyBaseID:	FBgn0011701	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_001004015.1	Gene:	lhx6a / 445565	ZFINID:	ZDB-GENE-041025-1	Length:	375	Species:	Danio rerio

Alignment Length:	166	Identity:	49/166 - (29%)
Similarity:	75/166 - (45%)	Gaps:	26/166 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   271 IQGAAGTAGGVAAPAAKKDGSSSKKKGDPNGIKKKKTRTTFTAYQLEELERAFERAPYPDVFARE 335
            ::.||.:..|:....|......|:.|      ..|:.||:|||.||:.::..|.:...||....:
Zfish   219 LKRAAESGSGLTLEGAVPSEQDSQPK------PAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQ 277

  Fly   336 ELAIKLNLSESRVQVWFQNRRAKWRKHEPPRKTGYIKTSTPPTATLNPGTLAPPFTSYPQTTTVT 400
            :||....||...:||||||.||:.:||.|       :.:.||.|  :|....||  |.|.....:
Zfish   278 KLADMTGLSRRVIQVWFQNCRARHKKHTP-------QHNGPPQA--HPQARMPP--SLPDELHYS 331

  Fly   401 PPGS-----MDSWTSYQTPYELTPQFSLLSPAASPY 431
            |.||     |.:...|...:    .||:|:..:.|:
Zfish   332 PFGSPERARMVALHGYIDSH----PFSVLTTQSLPH 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
repo	NP_477026.1	Homeobox	313..360	CDD:278475	18/46 (39%)
lhx6a	NP_001004015.1	LIM1_Lhx6	97..150	CDD:188766
		LIM2_Lhx6	158..212	CDD:188768
		Homeobox	250..302	CDD:278475	22/51 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940