DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment repo and eyg

DIOPT Version :9

Sequence 1:	NP_477026.1	Gene:	repo / 47285	FlyBaseID:	FBgn0011701	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_001014582.1	Gene:	eyg / 39419	FlyBaseID:	FBgn0000625	Length:	670	Species:	Drosophila melanogaster

Alignment Length:	428	Identity:	116/428 - (27%)
Similarity:	160/428 - (37%)	Gaps:	121/428 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   237 GGAGVTPPSSSSTVVNGTTNGTGNANSSSSAGVGIQGA---------AGTAGGVAAPAAKKDGSS 292
            ||.||.||...|.:.:.......|...|:::.|.:...         ||.|||.....|...||.
  Fly   257 GGQGVPPPPPPSALWSVAAPTLANLPPSAASAVPVSTCGSLSSAHLMAGGAGGTPTNRAISPGSG 321

  Fly   293 SKKK---------------GDPNGIKKKKTRTTFTAYQLEELERAFERAPYPDVFAREELAIKLN 342
            |...               .|.:..|.::.||||:..||||||:.|:::.||.|..||.|:.:.:
  Fly   322 SHDTLESADENRHIDSDYLDDDDEPKFRRNRTTFSPEQLEELEKEFDKSHYPCVSTRERLSSRTS 386

  Fly   343 LSESRVQVWFQNRRAKWRKHE-----------PPRKTGYIKTSTPPTATLNPGTLAPPFTSYPQT 396
            |||:||||||.|||||||:|:           |.......:::..|.::..|...:...||.| .
  Fly   387 LSEARVQVWFSNRRAKWRRHQRMNLLKRQRSSPANPLHSQQSNDAPASSPTPSNHSSASTSAP-V 450

  Fly   397 TTVTPPGSMDSWTSYQTPYEL--------TPQFSLLSPAASPYGTYSGQYGAYV--HESQLFPMR 451
            ..|.||         |.|..|        .|...||.|...|.|.:...:..::  |.:.|..:.
  Fly   451 APVPPP---------QQPLPLCGDHSPQGPPPSVLLHPLHGPPGGHHHHHPLHLPTHPAALQLLS 506

  Fly   452 HYEYGSPTRMEMGATTGSVAGNGDESVANGGSYQTAELQTAQQQQLADGTLVTVHAHQQQQ--QQ 514
            ||.                                .:.|..||||         |..||||  ||
  Fly   507 HYH--------------------------------QQQQQQQQQQ---------HQQQQQQHHQQ 530

  Fly   515 QQQL---------NGKYLSAEEAKYVHLQCHQSGG---GLELSPGASCHLVEAQGQ----HYVTT 563
            ||||         |...:..|.:.:..|....|..   ||......:..|..|:.|    ||
  Fly   531 QQQLSPSGCNPAANHLSMGGERSAFRSLVSSPSAAAFLGLARQYAVAASLTVAEEQRSRLHY--- 592

  Fly   564 ATGGAASAG---GTSSDDNDSGG-MQTVIKSEEVSQQQ 597
            :.||..|.|   |.:::...||| ..||..|...|.::
  Fly   593 SAGGLGSGGEGTGPNTNTTQSGGSTMTVDNSSSDSDEE 630

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
repo	NP_477026.1	Homeobox	313..360	CDD:278475	27/46 (59%)
eyg	NP_001014582.1	HTH	120..217	CDD:304362
eyg	NP_001014582.1	Homeobox	352..404	CDD:278475	31/51 (61%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450824
Domainoid	1	1.000	55	1.000	Domainoid score	I4097
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840