DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment repo and lhx8a

DIOPT Version :9

Sequence 1:	NP_477026.1	Gene:	repo / 47285	FlyBaseID:	FBgn0011701	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_001003980.1	Gene:	lhx8a / 378959	ZFINID:	ZDB-GENE-031008-2	Length:	332	Species:	Danio rerio

Alignment Length:	158	Identity:	45/158 - (28%)
Similarity:	68/158 - (43%)	Gaps:	27/158 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   268 GVGIQGAAGTAGGVAAPAAKKDGSSSKKKGDPNGIKKKKTRTTFTAYQLEELERAFERAPYPDVF 332
            ||.::||..:...|..|.                 ..|:.||:|||.||:.::..|.:...||..
Zfish   182 GVNVEGAVPSEQEVNQPK-----------------PAKRARTSFTADQLQVMQAQFAQDNNPDAQ 229

  Fly   333 AREELAIKLNLSESRVQVWFQNRRAKWRKHEPPRKTGYIKTSTPPTATLNPGTLAPPFTSYPQTT 397
            ..::||.:..||...:||||||.||:.:||..|.     .:|..|.::|....|:||.....|.|
Zfish   230 TLQKLAERTGLSRRVIQVWFQNCRARHKKHVSPN-----HSSAAPVSSLQSAHLSPPLIDELQYT 289

  Fly   398 TVTPPG-----SMDSWTSYQTPYELTPQ 420
            ...|..     ::.|:....:|..|..|
Zfish   290 AFAPVDTPMLTALHSYMDVHSPTSLVLQ 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
repo	NP_477026.1	Homeobox	313..360	CDD:278475	18/46 (39%)
lhx8a	NP_001003980.1	LIM1_Lhx7_Lhx8	50..105	CDD:188767
		LIM2_Lhx7_Lhx8	112..166	CDD:188769
		Homeobox	205..257	CDD:278475	22/51 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000