DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment repo and Phox2b

DIOPT Version :9

Sequence 1:NP_477026.1 Gene:repo / 47285 FlyBaseID:FBgn0011701 Length:612 Species:Drosophila melanogaster
Sequence 2:XP_008768389.3 Gene:Phox2b / 364152 RGDID:1560582 Length:314 Species:Rattus norvegicus


Alignment Length:174 Identity:62/174 - (35%)
Similarity:79/174 - (45%) Gaps:44/174 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   263 SSSSAGVGIQ------------GAAGTAGGVAAPAAKKDGSSS-------KKKGDPNGI----KK 304
            ||.|...|.|            |......|..:....:|..||       |...|..|:    |:
  Rat    34 SSCSQASGFQYNPIRTTFGATSGCPSLTPGSCSLGTLRDHQSSPYAAVPYKLFTDHGGLNEKRKQ 98

  Fly   305 KKTRTTFTAYQLEELERAFERAPYPDVFAREELAIKLNLSESRVQVWFQNRRAKWRKHE------ 363
            ::.|||||:.||:||||.|....|||::.|||||:|::|:|:||||||||||||:||.|      
  Rat    99 RRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAAAAA 163

  Fly   364 -PPRKTGYI--------------KTSTPPTATLNPGTLAPPFTS 392
             ...|.|..              ..||.|.:|..||....|..|
  Rat   164 AAAAKNGSSGKKSDSSRDDESKEAKSTDPDSTGGPGPNPNPTPS 207

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
repoNP_477026.1 Homeobox 313..360 CDD:278475 30/46 (65%)
Phox2bXP_008768389.3 Homeobox 102..155 CDD:395001 35/52 (67%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000011
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
22.000

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