DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment repo and arxa

DIOPT Version :9

Sequence 1:	NP_477026.1	Gene:	repo / 47285	FlyBaseID:	FBgn0011701	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_571459.1	Gene:	arxa / 30657	ZFINID:	ZDB-GENE-990415-15	Length:	453	Species:	Danio rerio

Alignment Length:	360	Identity:	107/360 - (29%)
Similarity:	147/360 - (40%)	Gaps:	109/360 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 SSSPKDQYEPQQLQHLYGGSPHHLD-------HLDHGSDGLLQDSS----------PVMINGG-- 218
            :|...|.:.|.:|:.|||....:||       ||:.|....|.|.:          .|.|:..
Zfish    67 NSFDSDMHLPPKLRRLYGPGGKYLDSGRGFHEHLEKGERERLLDQACESLKISQAPQVSISRSKS 131

  Fly   219 -------SAGGKLKKPDEMCSQL---------------EAGGAGVTPPSSSSTVVNGTTNGTGNA 261
                   |...:.:.|:.|..:|               ||.|.....|....::.|......|..
Zfish   132 YRENAPFSQSDEGQSPEHMAQELVELSTLKFEEDVVKEEACGDNSLSPKDEESLHNDGDVKDGED 196

  Fly   262 NSSSSAGVGIQGAAGTAGGVAAPAAKKDGSSSKKKGDPNGIKKKKTRTTFTAYQLEELERAFERA 326
            :...|||                :..::|...:        |:::.|||||:||||||||||::.
Zfish   197 SVCLSAG----------------SDSEEGMLKR--------KQRRYRTTFTSYQLEELERAFQKT 237

  Fly   327 PYPDVFAREELAIKLNLSESRVQVWFQNRRAKWRKHEPPRKTGYIKTSTPPTATLNPGTLAP--- 388
            .|||||.|||||::|:|:|:|||||||||||||||.|   |.|   ....||....||.||.
Zfish   238 HYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKRE---KAG---VQAHPTGLPFPGPLAAAHP 296

  Fly   389 --------PFTSYPQTTTVTPPGSMDSWTSYQT-----PYELTPQFSLLSPAASP--YGTYSGQY 438
                    ||..:|.      |....:||:...     |....|..|...|.|:|  .||:.|
Zfish   297 LSHYLEGGPFPPHPH------PALESAWTAAAAAAAAFPGLAPPPNSSALPPATPLGLGTFLG-- 353

  Fly   439 GAYVHESQLFPMRHYEYGSPT--RM--EMGATTGS 469
                  :.:|  ||..:..||  |:  .||..|.:
Zfish   354 ------TAMF--RHPAFIGPTFGRLFSSMGPLTSA 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
repo	NP_477026.1	Homeobox	313..360	CDD:278475	35/46 (76%)
arxa	NP_571459.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	49..75		2/7 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	124..149		4/24 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	170..212		10/57 (18%)
		Homeobox	219..271	CDD:278475	40/51 (78%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	390..418
		OAR	417..434	CDD:281777
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	421..434
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24329
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	3	2.970