Protein Alignment repo and pax3a

DIOPT Version :10

• Sequence 1: NP_477026.1
• Gene: repo / 47285
• FlyBaseID: FBgn0011701
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_571352.1
• Gene: pax3a / 30532
• ZFINID: ZDB-GENE-980526-52
• Length: 509
• Species: Danio rerio
• Alignment Length: 549
• Identity: 145/549 - (26%)
• Similarity: 200/549 - (36%)
• Gaps: 154/549 - (28%)

  Fly   132 TPPPSH--NGILLHKQSSQQQQQQQQQLVGILDYHPLNGKLDYSSSPKDQYEPQQLQHLYGGSPH 194
            |||.::  .|..| :.|:...|.:..||.|:.    :||:      |.    |..::|......|
Zfish    15 TPPQNYPRGGYSL-EVSTPLGQGRVNQLGGVF----INGR------PL----PNHIRHKIVEMAH 64

  Fly   195 H---------LDHLDHG--SDGLLQDSSPVMINGGSAGGKLKK----PD---------------- 228
            |         ...:.||  |..|.:......|..|:.||...|    ||
Zfish    65 HGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQSTTPDVEKKIEEYKRENPGMF 129

  Fly   229 --EMCSQLEAGGA----GVTPPSSSSTVVNGTTNGTGNANSSSS-------------AGVGIQGA 274
              |:..:|...|.    .|...||.|.::.....|.|:.:....             |...|.|.
Zfish   130 SWEIRDKLLKDGICDRNNVPSVSSISRMLRCKFGGNGDEDEDDDEVEKREIEENERRAKHSIDGI 194

  Fly   275 AGTAGGVAAPAAKKDGSS-SKKKGDPNGIKKKKTRTTFTAYQLEELERAFERAPYPDVFAREELA 338
            .|...     :...:||. ..:.|.|...|::::||||||.|||||||||||..|||::.|||||
Zfish   195 LGDRS-----SHSDEGSDVDSEPGLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELA 254

  Fly   339 IKLNLSESRVQVWFQNRRAKWRKHEPPRK----TGYIKTSTPPTA--TLNPGTLAPPFTSYP--- 394
            .:..|:|:||||||.||||:|||.....:    ...|....||:|  :|.|..||.  :.||
Zfish   255 QRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPSAMSSLQPYQLAD--SPYPPSS 317

  Fly   395 ------QTTTVTPPGSMDSWTSYQTPYELTPQFSLLSPAASPYGTYSGQYGAYVHESQLFPMRHY 453
                  |.:||..|..:...:.:|:.....|.   ....:|.|...||::|.
Zfish   318 ISQVSEQPSTVHRPQPLPPTSVHQSGLGSGPG---AQEGSSAYCLSSGRHGF------------- 366

  Fly   454 EYGSPTRMEMGATTGSVAGNG-----DESVANGGSYQTAELQTAQQQQLADGTLVTVHAHQQQQQ 513
                     .|.:.|.||..|     :.|::||...|...|       |..|.:    .||.|..
Zfish   367 ---------SGYSDGYVAAPGHANPVNPSISNGLPSQVMGL-------LNPGAV----PHQPQSD 411

  Fly   514 -QQQQLNGKYLSAEEAKYVHLQCHQSGGGLELSPGASCHLVEAQGQHYVTTATGGAASAGGTSSD 577
             ....|.|   ..|.:..:...|| |...||..||..........|.|..:    :.|:.|.|.|
Zfish   412 FALSPLTG---GLEPSTGMPASCH-SSQRLEALPGLPSMPALPSSQSYCPS----SYSSPGYSVD 468

  Fly   578 DNDSGGMQTVIKSEEVSQQQQQQQGQSYV 606
                          .|:..|..|.|||.|
Zfish   469 --------------HVASYQYSQYGQSKV 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
repo	NP_477026.1	Homeodomain	313..361	CDD:459649	33/47 (70%)
pax3a	NP_571352.1	PAX	34..159	CDD:128645	29/138 (21%)
		Homeodomain	221..277	CDD:459649	38/55 (69%)
		Pax7	350..394	CDD:403540	13/65 (20%)