Protein Alignment repo and RAX

DIOPT Version :10

• Sequence 1: NP_477026.1
• Gene: repo / 47285
• FlyBaseID: FBgn0011701
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_038463.2
• Gene: RAX / 30062
• HGNCID: 18662
• Length: 346
• Species: Homo sapiens
• Alignment Length: 309
• Identity: 93/309 - (30%)
• Similarity: 123/309 - (39%)
• Gaps: 95/309 - (30%)

  Fly   190 GGSPHHLDHLD-----HGSDGLLQDSSPVMINGGSAGGKLK------KPDEMCSQLEAGGAGVTP 243
            |||...|..::     ...||:| .:.|.  ..|:.|.|.:      :|  .|.:....|:..:|
Human    26 GGSTSRLHSIEAILGFTKDDGIL-GTFPA--ERGARGAKERDRRLGARP--ACPKAPEEGSEPSP 85

  Fly   244 PSSSSTVVNGTT------NGTGNANSSSSAGVGIQGAAGTAGGVAAPAAKKDGSSSKKKGDPNGI 302
            |.:.:.......      ...|.|..|          .|...|.|...||.......||
Human    86 PPAPAPAPEYEAPRPYCPKEPGEARPS----------PGLPVGPATGEAKLSEEEQPKK------ 134

  Fly   303 KKKKTRTTFTAYQLEELERAFERAPYPDVFAREELAIKLNLSESRVQVWFQNRRAKWRKHEPPRK 367
            |.::.|||||.|||.|||||||::.||||::|||||.|:||.|.||||||||||||||:.| ..:
Human   135 KHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQE-KLE 198

  Fly   368 TGYIK---------TSTPPTATLNP-------------GTL------------------------ 386
            ...:|         :.:||:|||:|             |.|
Human   199 VSSMKLQDSPLLSFSRSPPSATLSPLGAGPGSGGGPAGGALPLESWLGPPLPGGGATALQSLPGF 263

  Fly   387 APPFTSYPQTTTVTPPGSMDSWTSYQTPYELTPQFSL-LSPAASPYGTY 434
            .||..|.|.:.|..||         ..|:..:|.... |.|.|.|..:|
Human   264 GPPAQSLPASYTPPPP---------PPPFLNSPPLGPGLQPLAPPPPSY 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
repo	NP_477026.1	Homeodomain	313..361	CDD:459649	36/47 (77%)
RAX	NP_038463.2	Octapeptide motif	33..40		0/6 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	46..145		26/119 (22%)
		Homeodomain	137..193	CDD:459649	41/55 (75%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..318		24/120 (20%)
		OAR	319..335	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	323..336
		Nuclear localization signal. /evidence=ECO:0000255	329..333