DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment repo and LHX6

DIOPT Version :9

Sequence 1:	NP_477026.1	Gene:	repo / 47285	FlyBaseID:	FBgn0011701	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	XP_011516823.1	Gene:	LHX6 / 26468	HGNCID:	21735	Length:	407	Species:	Homo sapiens

Alignment Length:	142	Identity:	43/142 - (30%)
Similarity:	66/142 - (46%)	Gaps:	15/142 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   271 IQGAAGTAGGVAAPAAKKDGSSSKKKGDPNGIKKKKTRTTFTAYQLEELERAFERAPYPDVFARE 335
            ::.||....|:....|......|:.|      ..|:.||:|||.||:.::..|.:...||....:
Human   221 LKRAAENGNGLTLEGAVPSEQDSQPK------PAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQ 279

  Fly   336 ELAIKLNLSESRVQVWFQNRRAKWRKHEPPRKTGYIKTSTPPTATLNPGTLA-----PPFTSYPQ 395
            :||....||...:||||||.||:.:||.|...   :..|..|.:.| |..|:     .||:|..:
Human   280 KLADMTGLSRRVIQVWFQNCRARHKKHTPQHP---VPPSGAPPSRL-PSALSDDIHYTPFSSPER 340

  Fly   396 TTTVTPPGSMDS 407
            ...||..|.:::
Human   341 ARMVTLHGYIET 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
repo	NP_477026.1	Homeobox	313..360	CDD:278475	18/46 (39%)
LHX6	XP_011516823.1	LIM1_Lhx6	99..152	CDD:188766
		LIM2_Lhx6	160..214	CDD:188768
		Homeobox	252..304	CDD:278475	22/51 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940