DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment repo and Pitx3

DIOPT Version :9

Sequence 1:	NP_477026.1	Gene:	repo / 47285	FlyBaseID:	FBgn0011701	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	XP_006526827.1	Gene:	Pitx3 / 18742	MGIID:	1100498	Length:	388	Species:	Mus musculus

Alignment Length:	230	Identity:	73/230 - (31%)
Similarity:	103/230 - (44%)	Gaps:	52/230 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   243 PPSSSSTVVNGTTNGTGNANSSSSAGV--------GIQG---------AAGTAGGVAAPAAKKDG 290
            |||....:: |.......|.|.|.||.        |.:|         :|...||     :.:||
Mouse    84 PPSMEFGLL-GEAEARSPALSLSDAGTPHPPLPEHGCKGQEHSDSEKASASLPGG-----SPEDG 142

  Fly   291 SSSKKKGDPNGIKKKKTRTTFTAYQLEELERAFERAPYPDVFAREELAIKLNLSESRVQVWFQNR 355
            |..|        |:::.||.||:.||:|||..|:|..|||:..|||:|:..||:|:||:|||:||
Mouse   143 SLKK--------KQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNR 199

  Fly   356 RAKWRKHEPPRKTGYIKTS--------TPPTATLNPG---------TLAPPFT--SYPQTTTVTP 401
            ||||||.|..::....|..        .||...:.||         .||||..  ::|.......
Mouse   200 RAKWRKRERSQQAELCKGGFAAPLGGLVPPYEEVYPGYSYGNWPPKALAPPLAAKTFPFAFNSVN 264

  Fly   402 PGSMDSWTSYQTPYELTPQFSLLSPAASPYGTYSG 436
            .|.:.|...:..|..:..  |::..||:..||..|
Mouse   265 VGPLASQPVFSPPSSIAA--SMVPSAAAAPGTVPG 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
repo	NP_477026.1	Homeobox	313..360	CDD:278475	27/46 (59%)
Pitx3	XP_006526827.1	Homeobox	152..205	CDD:365835	32/52 (62%)
		PTZ00395	<228..>322	CDD:185594	18/72 (25%)
		OAR	344..361	CDD:367680
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.940