Protein Alignment repo and Pitx2

DIOPT Version :10

• Sequence 1: NP_477026.1
• Gene: repo / 47285
• FlyBaseID: FBgn0011701
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_001035967.1
• Gene: Pitx2 / 18741
• MGIID: 109340
• Length: 324
• Species: Mus musculus
• Alignment Length: 297
• Identity: 84/297 - (28%)
• Similarity: 127/297 - (42%)
• Gaps: 56/297 - (18%)

  Fly   212 PVMINGGSAGGKLKKPDE-MCSQLEA-GGAGVTPPSSSSTVVNGTTNGTGNANSSSSAGVGIQGA 274
            |:.:...:||.||..... .|...:| ..|.|..|            |...:..||...:.:...
Mouse     7 PLPLEHRAAGTKLSAASSPFCHHPQALAMASVLAP------------GQPRSLDSSKHRLEVHTI 59

  Fly   275 AGTAGGVAAPAAKKD-GSSSKKKG----DPNGIKK-KKTRTTFTAYQLEELERAFERAPYPDVFA 333
            :.|:   :...|:|| |...|.:.    ||:..|: ::.||.||:.||:|||..|:|..|||:..
Mouse    60 SDTS---SPEVAEKDKGQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMST 121

  Fly   334 REELAIKLNLSESRVQVWFQNRRAKWRKHEPPRKTGYIKTSTPPTATLNPGTLAPPFTSYPQTTT 398
            |||:|:..||:|:||:|||:||||||||.|..::           |.|......|.|....|...
Mouse   122 REEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----------AELCKNGFGPQFNGLMQPYD 175

  Fly   399 VTPPG-SMDSW-----TSYQTPYELTPQFSLLSPAASPYGTYSGQYGAYVHESQLF--PMRHYEY 455
            ...|| |.::|     ||.....:..|.|:.::  .:|..:.|           :|  |......
Mouse   176 DMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMN--VNPLSSQS-----------MFSPPNSISSM 227

  Fly   456 GSPTRMEMGATTGSVAGNGDESVANGGSYQTAELQTA 492
            ...:.|...|.|| |.|:...|:.|..:..:..|.:|
Mouse   228 SMSSSMVPSAVTG-VPGSSLNSLNNLNNLSSPSLNSA 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
repo	NP_477026.1	Homeodomain	313..361	CDD:459649	28/47 (60%)
Pitx2	NP_001035967.1	Homeodomain	93..149	CDD:459649	32/55 (58%)
		OAR	282..299	CDD:461067