DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment repo and Pax6

DIOPT Version :9

Sequence 1:	NP_477026.1	Gene:	repo / 47285	FlyBaseID:	FBgn0011701	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_001231127.1	Gene:	Pax6 / 18508	MGIID:	97490	Length:	436	Species:	Mus musculus

Alignment Length:	303	Identity:	88/303 - (29%)
Similarity:	126/303 - (41%)	Gaps:	80/303 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   202 GSDGLLQDSSPVMING--GSAGGKL----------KKPDEMCSQLEAGGAGVTPPSSSSTVVNGT 254
            |:||:.....  |:||  ||.|.:.          :...:.|.|.|.||.
Mouse   152 GADGMYDKLR--MLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGE--------------- 199

  Fly   255 TNGTGNANSSSSAGVGIQGAAGTAGGVAAPAAKKDGSSSKKKGDPNGIKKK--KTRTTFTAYQLE 317
                 |.||.||.|                   :|...::.:..   :|:|  :.||:||..|:|
Mouse   200 -----NTNSISSNG-------------------EDSDEAQMRLQ---LKRKLQRNRTSFTQEQIE 237

  Fly   318 ELERAFERAPYPDVFAREELAIKLNLSESRVQVWFQNRRAKWRKHEPPRKTGYIKTSTPPTATLN 382
            .||:.|||..||||||||.||.|::|.|:|:||||.|||||||:.|..|......::||....::
Mouse   238 ALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPIS 302

  Fly   383 PGTLAPPFTSYPQTTTVTPPGSMDSWTSY-QTPYELTPQFSLLSPAAS-----------PYGTYS 435
            .......:...||.|  ||..|..|.:.. :|...||..:|.|.|..|           |..:.:
Mouse   303 SSFSTSVYQPIPQPT--TPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQT 365

  Fly   436 GQYGAYVHESQLFPMRHYEYGSPTRME-------MGATTGSVA 471
            ..|...:..|.....|.|:..:|..|:       || |:|:.:
Mouse   366 SSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMG-TSGTTS 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
repo	NP_477026.1	Homeobox	313..360	CDD:278475	30/46 (65%)
Pax6	NP_001231127.1	PAX	4..142	CDD:128645
Pax6	NP_001231127.1	Homeobox	228..281	CDD:395001	35/52 (67%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.940