Protein Alignment repo and Otx2

DIOPT Version :10

• Sequence 1: NP_477026.1
• Gene: repo / 47285
• FlyBaseID: FBgn0011701
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_001273410.1
• Gene: Otx2 / 18424
• MGIID: 97451
• Length: 297
• Species: Mus musculus
• Alignment Length: 272
• Identity: 85/272 - (31%)
• Similarity: 119/272 - (43%)
• Gaps: 68/272 - (25%)

  Fly   243 PPSSSSTVVNG---TTNGTGNANSSSSAGVGIQGAAGTAGGVAAPAAKKDGSSSKKKGDPNGIKK 304
            ||.:    |||   ||:|....:.|    ||..|.     ..:.|||           .|.  |:
Mouse     8 PPYA----VNGLSLTTSGMDLLHPS----VGYPGP-----WASCPAA-----------TPR--KQ 46

  Fly   305 KKTRTTFTAYQLEELERAFERAPYPDVFAREELAIKLNLSESRVQVWFQNRRAKWRKHEPPRKTG 369
            ::.|||||..||:.||..|.:..|||:|.|||:|:|:||.||||||||:|||||.|:.:..::.|
Mouse    47 RRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNG 111

  Fly   370 YIKTSTPPTATLNP-----------GTLAPP-FTSYPQTTTVTPPGSMDSWTSYQTPYELTPQFS 422
            ......|.....:|           |..:|| .||.|...:.:.|.|:  |    :|..::|...
Mouse   112 GQNKVRPAKKKSSPAREVSSESGTSGQFSPPSSTSVPTIASSSAPVSI--W----SPASISPLSD 170

  Fly   423 LLSPAAS--------PYGTYSGQYGAYVHESQLF----------PMRHYEYG-SPTRMEMGATTG 468
            .||.::|        .|...||....|...:..|          ||.|...| ..|...||  |.
Mouse   171 PLSTSSSCMQRSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMG--TN 233

  Fly   469 SVAGNGDESVAN 480
            :|..:.::|.|:
Mouse   234 AVTSHLNQSPAS 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
repo	NP_477026.1	Homeodomain	313..361	CDD:459649	29/47 (62%)
Otx2	NP_001273410.1	Homeodomain	47..102	CDD:459649	34/54 (63%)
		TF_Otx	161..242	CDD:427350	19/82 (23%)