DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment repo and dmbx1a

DIOPT Version :9

Sequence 1:	NP_477026.1	Gene:	repo / 47285	FlyBaseID:	FBgn0011701	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_694509.1	Gene:	dmbx1a / 142987	ZFINID:	ZDB-GENE-020117-1	Length:	388	Species:	Danio rerio

Alignment Length:	334	Identity:	81/334 - (24%)
Similarity:	115/334 - (34%)	Gaps:	106/334 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   303 KKKKTRTTFTAYQLEELERAFERAPYPDVFAREELAIKLNLSESRVQVWFQNRRAKWRK------ 361
            |::::||.|||.|||.||:.|::..||||..||.||:..||.|:||||||:|||||:||
Zfish    70 KQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQ 134

  Fly   362 -------------------------------HEPPRKTGYIKTSTPPTATLNPGTLAPPFTSYPQ 395
                                           ::||..|   .:|:...|...|..|....:....
Zfish   135 KEQLQKQKDVSTDGALAASDKDEAPSTLNLENQPPSST---SSSSSMEAEAAPHALGSELSVELN 196

  Fly   396 TTTVTPPGSMDSWTSYQT--------------------PYELTPQFSLLSPAA-SPYG------T 433
            .|:....||..:.....|                    |..|:|....|||.. ||.|      :
Zfish   197 VTSAEQSGSESATEDNATDKEEEIKQHREDLKVEKEPAPGNLSPLCKRLSPKPDSPLGSPAISSS 261

  Fly   434 YSGQYG--AYVHESQLFPMRHYEYGSPTRMEMGATTGSVAGNGDESVANGGSYQTAELQTAQ--- 493
            .||..|  :..|.....|:..:......|..|.||...|            .|.:.::.|..
Zfish   262 SSGVTGGISQSHSYSSSPLSLFRLQEQFRQHMAATNNLV------------HYPSFDMATPSSIP 314

  Fly   494 ------QQQLADGTLVTVHAHQQQQQQQQQL---------------NGKYLSAEEAKYVHLQCHQ 537
                  ......|:|.....:|......||:               |.|..|.|..: :..:.|.
Zfish   315 YLGMNVNMPAPLGSLPCQSYYQSLSHHAQQVWNSPLLQASGGLPSHNSKTTSIENLR-LRAKQHA 378

  Fly   538 SGGGLELSP 546
            :..||:..|
Zfish   379 ASLGLDTLP 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
repo	NP_477026.1	Homeobox	313..360	CDD:278475	29/46 (63%)
dmbx1a	NP_694509.1	Homeobox	74..127	CDD:278475	33/52 (63%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	129..272		23/145 (16%)
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	365..378		2/13 (15%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.030