DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment repo and Phox2a

DIOPT Version :9

Sequence 1:	NP_477026.1	Gene:	repo / 47285	FlyBaseID:	FBgn0011701	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_032913.1	Gene:	Phox2a / 11859	MGIID:	106633	Length:	280	Species:	Mus musculus

Alignment Length:	274	Identity:	83/274 - (30%)
Similarity:	111/274 - (40%)	Gaps:	85/274 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   266 SAGVGIQGAAGTAGG-----------VAAPAAKKDGSSSKKKG-------------------DPN 300
            ::..|..||....||           .|.|.....|||:...|                   :|:
Mouse    18 ASAYGDFGACSQPGGFQYSPLRPAFPAAGPPCPALGSSNCALGALRDHQPAPYSAVPYKFFPEPS 82

  Fly   301 GI----KKKKTRTTFTAYQLEELERAFERAPYPDVFAREELAIKLNLSESRVQVWFQNRRAKWRK 361
            |:    |:::.|||||:.||:||||.|....|||::.|||||:|::|:|:||||||||||||:||
Mouse    83 GLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRK 147

  Fly   362 HE-----------PPRKTGYIKTSTPPTATLNPGTLAPPFTSYPQTTTVTPPGSMDSWTSYQTPY 415
            .|           ...|.|..:.|:....: ...|.:|.    |.:|...||....|..|
Mouse   148 QERAASAKGAAGATGAKKGEARCSSEDDDS-KESTCSPT----PDSTASLPPPPAPSLAS----- 202

  Fly   416 ELTPQFSLLSPAASPYGTYSGQYGAYVHESQLFPMRHYEYGSPTRMEMGATTGSVAGNGDESVAN 480
               |:   |||:..|....||.                   .|..:: ||....|||.|......
Mouse   203 ---PR---LSPSPLPAALGSGP-------------------GPQPLK-GALWAGVAGGGGGGPGT 241

  Fly   481 GGSYQTAELQTAQQ 494
            |    .|||..|.|
Mouse   242 G----AAELLKAWQ 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
repo	NP_477026.1	Homeobox	313..360	CDD:278475	30/46 (65%)
Phox2a	NP_032913.1	Homeobox	94..147	CDD:395001	35/52 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	145..244		29/138 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	260..280
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000