DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment repo and Alx3

DIOPT Version :9

Sequence 1:	NP_477026.1	Gene:	repo / 47285	FlyBaseID:	FBgn0011701	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_031467.1	Gene:	Alx3 / 11694	MGIID:	1277097	Length:	343	Species:	Mus musculus

Alignment Length:	289	Identity:	84/289 - (29%)
Similarity:	127/289 - (43%)	Gaps:	49/289 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   175 SPKDQYEPQQLQHLYGGSPH---------------HLDHLDHGSDGLLQDSSP-VMINGGSAGGK 223
            :|..|..|....||:...|.               :|..........|||..| .::|||.....
Mouse    25 APGPQGTPDAAPHLHPAPPRGPRLSRFPACGPLEPYLPEPAKPPAKYLQDLGPGPVLNGGHFYEG 89

  Fly   224 LKKPDEMCSQLEAGGAGVTPPSSSSTVVNGTTNGTGNANSSSS---AGVGIQGAAGTAGGVAAPA 285
            ..:.:|..|:      ..:.|........|..:|..|..:|..   |.:.:..:.|....:....
Mouse    90 SAEAEEKASK------AASFPQLPVDCRGGPRDGPSNVQASPGPCLASLSVPLSPGLPDSMELAK 148

  Fly   286 AKKDGSSSKKKGDPNGIKKKKTRTTFTAYQLEELERAFERAPYPDVFAREELAIKLNLSESRVQV 350
            .|.              ||::.||||:.:||||||:.|::..||||:|||:||::.:|:|:||||
Mouse   149 TKS--------------KKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQV 199

  Fly   351 WFQNRRAKWRKHEPPRKTGYIKTSTPPTATLNPGTLAPPFTSYPQ-TTTVTP-PGSMDSWTSYQT 413
            |||||||||||.|   :.|.::....|..|....::.|...|:|| ..::.| |||    .|...
Mouse   200 WFQNRRAKWRKRE---RYGKMQEGRNPFTTAYDISVLPRTDSHPQLQNSLWPSPGS----GSPGG 257

  Fly   414 PYELTPQFSLLSPAASPYGTYSGQYGAYV 442
            |..::|: .:.||..|||....|....::
Mouse   258 PCLMSPE-GIPSPCMSPYSHSHGNVAGFM 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
repo	NP_477026.1	Homeobox	313..360	CDD:278475	30/46 (65%)
Alx3	NP_031467.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..122		20/102 (20%)
		SP2	32..>141	CDD:281067	21/114 (18%)
		Homeobox	157..209	CDD:278475	34/51 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	309..343
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24329
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	4	3.970