DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment repo and arxb

DIOPT Version :9

Sequence 1:	NP_477026.1	Gene:	repo / 47285	FlyBaseID:	FBgn0011701	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	XP_002667096.1	Gene:	arxb / 100329907	ZFINID:	ZDB-GENE-121109-2	Length:	385	Species:	Danio rerio

Alignment Length:	386	Identity:	114/386 - (29%)
Similarity:	162/386 - (41%)	Gaps:	90/386 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 SSQQQQQQQQQ------LVGILDYHPLNGKLDYSSSPKDQYEPQQLQHLYGGSPH-HLDHLDHGS 203
            ||:.::...:|      ...:|..:.::..|...|..|.|..|..|..|:   || ||.......
Zfish     2 SSEVEEDNPEQTNCRCKTPTLLSSYCIDSILGRKSPLKVQETPHSLWPLH---PHMHLPPKLRRP 63

  Fly   204 DGLLQDSS------PVMINGGSAGGKLKKPDEMCSQLEAGGAGVTPPSSSSTVVN--------GT 254
            ...|.|||      |.::.  :|..|||..:.....:...|:.....|..:|.:|        |.
Zfish    64 FAPLTDSSTDETAGPRLLQ--TACEKLKITEASIVNISRAGSYQEHASCKNTPINEEEGADICGE 126

  Fly   255 TNGT----------GNANSSSSAGVGIQGAAGTAGGVAAPAAKKDGSSSKKKGDPNGIKKKKTRT 309
            ||.|          .:..:|.|||                :..:||...:        |:::.||
Zfish   127 TNVTLKQEREAFLKNSEETSLSAG----------------SDTEDGMLKR--------KQRRYRT 167

  Fly   310 TFTAYQLEELERAFERAPYPDVFAREELAIKLNLSESRVQVWFQNRRAKWRKHE----PPRKTGY 370
            |||:||||||||||::..|||||.|||||::|:|:|:|||||||||||||||.|    .|.....
Zfish   168 TFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKVGVQPHTLSL 232

  Fly   371 IKTSTPPTA-TLNPGTLAPPFTSYPQTTTVTPPGSMDSWTSYQTPYELTPQFSLLSPA---ASPY 431
            ..:..||.| :|.......||...|.      |....:|.:   |::     .|..||   .||.
Zfish   233 HYSGAPPAAQSLCHYLSGNPFVPNPH------PAIDSAWPA---PFQ-----RLAQPAQNSVSPP 283

  Fly   432 GTYSGQYGAYVHESQLFPMRHYEYGSPTRMEMGATTGSVAGNGDESVANGGSYQTAELQTA 492
            | :|...||.:       .||..:.:||...:..:.|.:|.......|..|..|.:.|.|:
Zfish   284 G-FSALLGAAM-------FRHPAFFNPTFGRLFTSLGPMALQRIPLPAIEGPIQRSHLTTS 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
repo	NP_477026.1	Homeobox	313..360	CDD:278475	35/46 (76%)
arxb	XP_002667096.1	Homeobox	166..218	CDD:278475	40/51 (78%)
arxb	XP_002667096.1	OAR	351..368	CDD:281777
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24329
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010