DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment repo and alx4a

DIOPT Version :9

Sequence 1:	NP_477026.1	Gene:	repo / 47285	FlyBaseID:	FBgn0011701	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	XP_001340966.1	Gene:	alx4a / 100006399	ZFINID:	ZDB-GENE-070712-3	Length:	368	Species:	Danio rerio

Alignment Length:	320	Identity:	103/320 - (32%)
Similarity:	138/320 - (43%)	Gaps:	93/320 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 SPVMI--NGGSAGGKLKKP-DEMCSQLEA-GGAGV--------------TPPSSSS-TVVNGTTN 256
            ||..:  .|...|.|...| .:.|..|:| .|.|.              |||.||. ...|...|
Zfish    45 SPAFLTNKGQGYGEKSGSPFQQECQSLDATAGEGTFNKYHLFMQRSSCKTPPDSSKLQQENSGHN 109

  Fly   257 G----------TGNANS-----SSSAGV----------GIQGAAGTAGGVAAPAAKKDGSSSKKK 296
            |          ||..:|     |..||:          |::........:|:|..|.:|.|:|.
Zfish   110 GGLIACYGKDSTGLTDSELPQNSDPAGMDGSYLSVKDSGVKSPQQATSELASPLDKTEGESNKG- 173

  Fly   297 GDPNGIKKKKTRTTFTAYQLEELERAFERAPYPDVFAREELAIKLNLSESRVQVWFQNRRAKWRK 361
                  ||::.|||||:|||||||:.|::..||||:|||:||::.:|:|:|||||||||||||||
Zfish   174 ------KKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRK 232

  Fly   362 HEPPRKTGYIKT--STP---PTAT--------LNPGTLAPPFTSYPQTTTVTPPGSMDSWTSYQT 413
            .|...:...::|  ||.   |..|        .||..:.....:.|....|.|   .||.||...
Zfish   233 RERFGQMQQVRTHFSTAYELPLLTRPENYAQIQNPSWIGGSSAASPVPGCVVP---CDSVTSCMP 294

  Fly   414 PYE-----LTPQFSLLSPAASPYGTYSGQYGAYVHESQLFPMRHYEYGSPTRMEMGATTG 468
            |:.     ::....:.||     |::.||    .|...||       |||     |..||
Zfish   295 PHPHAASGVSDFLGVPSP-----GSHMGQ----THMGSLF-------GSP-----GMGTG 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
repo	NP_477026.1	Homeobox	313..360	CDD:278475	31/46 (67%)
alx4a	XP_001340966.1	Homeobox	179..231	CDD:278475	36/51 (71%)
alx4a	XP_001340966.1	OAR	344..361	CDD:281777
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24329
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	4	3.970