DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SrpRbeta and srprb

DIOPT Version :9

Sequence 1:	NP_001261596.1	Gene:	SrpRbeta / 47283	FlyBaseID:	FBgn0011509	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_989042.2	Gene:	srprb / 394639	XenbaseID:	XB-GENE-952557	Length:	264	Species:	Xenopus tropicalis

Alignment Length:	241	Identity:	85/241 - (35%)
Similarity:	142/241 - (58%)	Gaps:	22/241 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 IDTGPIIVALLLGFIAVAIFVILRRRSAGRKDFLLTGLSESGKSAIFMQLIHGKFPATFTSIKEN 83
            :..|..::.::|.|:   ::.|||.....|:..||.|:.:|||:.:|.:|:.|.:..|.|||..|
Frog    31 LSVGIALIVVVLSFV---LWKILRGSRTSRRAVLLIGVCDSGKTLLFNRLLTGTYKKTQTSITAN 92

  Fly    84 VGDYRTGS---ASARLVDIPGHYRVRDKCLELYKHRAKGIVFVVDSVTAHKDIRDVADFLYTILS 145
            ...|:..:   :|..|||:|||..:|.:.||.||..|:.::|||||....:::::||:..|.:|:
Frog    93 CAAYKVKNDKGSSLTLVDLPGHESLRLQFLEQYKASARALLFVVDSSAFQREVKEVAELFYQLLT 157

  Fly   146 DSA----TQPCSVLVLCNKQDQTTAKSAQVIKSLLESELHTVRDTRSRKLQSVGDEDGSKSIT-L 205
            |.|    ..|  :|:.|||||.:.||||::|:..||.||:|:|.|||.....:  |.|:..:| |
Frog   158 DVAILKNVPP--ILIACNKQDISMAKSAKLIQQQLEKELNTLRVTRSAAPSIL--ESGNSGVTQL 218

  Fly   206 GKPGRDFEFSHIAQNIQFAEASAKDTE-------LDPLTDWLARLL 244
            ||.|:||:|:.:...::|.|.|.:|::       :..:..|||:|:
Frog   219 GKKGKDFDFTQLPMKVKFLECSTRDSKEEDGDANISNVEGWLAKLV 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SrpRbeta	NP_001261596.1	SR_beta	49..243	CDD:206691	77/208 (37%)
SrpRbeta	NP_001261596.1	SRPRB	51..221	CDD:255367	70/177 (40%)
srprb	NP_989042.2	SRPRB	55..234	CDD:370490	71/182 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	112	1.000	Domainoid score	I6155
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6332
Inparanoid	1	1.050	134	1.000	Inparanoid score	I4458
OMA	1	1.010	-	-		QHG54735
OrthoDB	1	1.010	-	-		D1503159at2759
OrthoFinder	1	1.000	-	-		FOG0004177
OrthoInspector	1	1.000	-	-		oto103396
Panther	1	1.100	-	-	LDO	PTHR11485
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3995
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.080