DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SrpRbeta and srp102

DIOPT Version :9

Sequence 1:	NP_001261596.1	Gene:	SrpRbeta / 47283	FlyBaseID:	FBgn0011509	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_593399.1	Gene:	srp102 / 2541760	PomBaseID:	SPAC23H4.07c	Length:	227	Species:	Schizosaccharomyces pombe

Alignment Length:	225	Identity:	64/225 - (28%)
Similarity:	116/225 - (51%)	Gaps:	28/225 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 IIVALLLGFIAVAIFVILRRRSAGRK--DFLLTGLSESGKSAIFMQLIHGKFPATFTSIKENVGD 86
            |:..:::|.|...:.:...|::..:|  ...|.|.|:|||:::|.:||:.:...|..||:.|...
pombe    11 IVATIIIGAIISTLGIFFTRKTIQKKLPAVFLIGPSDSGKTSLFCELIYKEKKTTVPSIEPNEAV 75

  Fly    87 YRTGSASARLVDIPGHYRVRDKCLELY--KHRAKGIVFVVDSVTAHKDIRDVADFLY-TILSDSA 148
            ::.|   |.|||:|||.|.:......:  .:..|.:|||::|.|..:|:.:|...|: |||....
pombe    76 WKYG---AWLVDLPGHPRAKRWITTKFSGNYNVKAVVFVLNSATIDRDVHEVGLMLFDTILKCRK 137

  Fly   149 TQPCSVLVLCNKQDQTTAKSAQVIKSLLESELHTVRDTRSRKLQSVGDEDGSKSITLGKPGRDFE 213
            .....:|:.|||.|..||:.|:.|:.||::|||.:.:.::.:|:|:..|             |.:
pombe   138 HHVPHLLIACNKFDLFTAQPAEKIQQLLKAELHNILEEKNLQLESIVSE-------------DVD 189

  Fly   214 FSHIAQNIQFAEASAKDTELDPLTDWLARL 243
            :..:|..|:       ||:|..|...:|::
pombe   190 WESVADQIE-------DTDLKFLPGSVAKM 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SrpRbeta	NP_001261596.1	SR_beta	49..243	CDD:206691	60/198 (30%)
SrpRbeta	NP_001261596.1	SRPRB	51..221	CDD:255367	53/172 (31%)
srp102	NP_593399.1	Srp102	3..214	CDD:225138	64/225 (28%)
srp102	NP_593399.1	SRPRB	35..209	CDD:255367	59/196 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	85	1.000	Domainoid score	I2216
eggNOG	1	0.900	-	-		E1_COG2229
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	90	1.000	Inparanoid score	I1748
OMA	1	1.010	-	-		QHG54735
OrthoFinder	1	1.000	-	-		FOG0004177
OrthoInspector	1	1.000	-	-		oto101059
orthoMCL	1	0.900	-	-		OOG6_103000
Panther	1	1.100	-	-	LDO	PTHR11485
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1394
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.860