DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SrpRbeta and Srprb

DIOPT Version :9

Sequence 1:	NP_001261596.1	Gene:	SrpRbeta / 47283	FlyBaseID:	FBgn0011509	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_033301.1	Gene:	Srprb / 20818	MGIID:	102964	Length:	269	Species:	Mus musculus

Alignment Length:	256	Identity:	92/256 - (35%)
Similarity:	146/256 - (57%)	Gaps:	21/256 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDKLNENARQRKQIKLGEIDTGPIIVALLLGFIAVAIFVILRRRSAGRKDFLLTGLSESGKSAIF 65
            :|.|.:..:||....|.      :.||||...:.:..:..:..|.:.::..|..||.:|||:.:|
Mouse    21 LDSLRQELQQRDPTLLS------VAVALLAVLLTLVFWKFIWSRKSSQRAVLFVGLCDSGKTLLF 79

  Fly    66 MQLIHGKFPATFTSIKENVGDYRTGS---ASARLVDIPGHYRVRDKCLELYKHRAKGIVFVVDSV 127
            ::|:.|::..|.|||.::...|:..:   .|..|:|:|||..:|.:.|:.:|..|:.:||||||.
Mouse    80 VRLLTGQYRDTQTSITDSSAIYKVNNNRGNSLTLIDLPGHESLRFQLLDRFKSSARAVVFVVDSA 144

  Fly   128 TAHKDIRDVADFLYTILSDS---ATQPCSVLVLCNKQDQTTAKSAQVIKSLLESELHTVRDTRSR 189
            ...::::|||:|||.:|.||   ...| |:|:.|||||...||||::|:..||.||:|:|.|||
Mouse   145 AFQREVKDVAEFLYQVLIDSMALKNSP-SLLIACNKQDIAMAKSAKLIQQQLEKELNTLRVTRS- 207

  Fly   190 KLQSVGDEDGSKSITLGKPGRDFEFSHIAQNIQFAEASAK----DT---ELDPLTDWLARL 243
            ...|..|...:....|||.|::||||.:...::|.|.|||    ||   ::..|..|||::
Mouse   208 AAPSTLDSSSTAPAQLGKKGKEFEFSQLPLKVEFLECSAKGGRGDTGSADIQDLEKWLAKI 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SrpRbeta	NP_001261596.1	SR_beta	49..243	CDD:206691	82/206 (40%)
SrpRbeta	NP_001261596.1	SRPRB	51..221	CDD:255367	71/175 (41%)
Srprb	NP_033301.1	SRPRB	60..239	CDD:255367	71/180 (39%)
Srprb	NP_033301.1	SR_beta	63..268	CDD:206691	82/206 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	125	1.000	Domainoid score	I5476
eggNOG	1	0.900	-	-		E1_COG2229
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6332
Inparanoid	1	1.050	149	1.000	Inparanoid score	I4376
Isobase	1	0.950	-	0.960964	Normalized mean entropy	S2424
OMA	1	1.010	-	-		QHG54735
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004177
OrthoInspector	1	1.000	-	-		oto93142
orthoMCL	1	0.900	-	-		OOG6_103000
Panther	1	1.100	-	-	LDO	PTHR11485
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1394
SonicParanoid	1	1.000	-	-		X3995
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.810