DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(3)05822 and BEM1

DIOPT Version :9

Sequence 1:	NP_001262702.1	Gene:	l(3)05822 / 47260	FlyBaseID:	FBgn0010877	Length:	600	Species:	Drosophila melanogaster
Sequence 2:	NP_009759.3	Gene:	BEM1 / 852499	SGDID:	S000000404	Length:	551	Species:	Saccharomyces cerevisiae

Alignment Length:	305	Identity:	60/305 - (19%)
Similarity:	101/305 - (33%)	Gaps:	73/305 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   276 SSDSNFSSPNNGSVSQPESGFEDDYHRSRPSTQSPLDPWEAVDSVGLGGVDSFGSAPVR----QT 336
            |:|.:..|.:||||                                   :....:.|||    .:
Yeast    21 SADISTPSHDNGSV-----------------------------------IKHIKTVPVRYLSSSS 50

  Fly   337 YQVQSRGSDNP--LCNGKSLLPPTQSLTMPTIIKPKISQKPKAPKPPPF-------IGGHLPPGY 392
            ..|:|:...:|  ..|.|.:..|.:      :||.|.|.:.:..|...|       :.|.....|
Yeast    51 TPVKSQRDSSPKNRHNSKDITSPEK------VIKAKYSYQAQTSKELSFMEGEFFYVSGDEKDWY 109

  Fly   393 SIPSGYAGSE-TPPSPPMPKGPPPPPPPASSGGISLLDVINGKVDALALSNGCQGYMEEEVVPYA 456
            ...:...|.| ..|...........|...:....|...|.|..::..:|              ||
Yeast   110 KASNPSTGKEGVVPKTYFEVFDRTKPSSVNGSNSSSRKVTNDSLNMGSL--------------YA 160

  Fly   457 VALYDFDGIEPGDLSFREGEKIYLLDHPTPEWLRGRT--RSGCEGIFPINYVDIKVPLGATGGAA 519
            :.||||...:..:|:...||.:::..|...||...:.  |.|..|:.|:.:|.| :.: |||.|.
Yeast   161 IVLYDFKAEKADELTTYVGENLFICAHHNCEWFIAKPIGRLGGPGLVPVGFVSI-IDI-ATGYAT 223

  Fly   520 AAPTASAAAPSPSPSQQQLPTALCLYHFPGEVEGDLALQENELVT 564
            .............|:.|:..:.:..|.......|.:..|:.:.:|
Yeast   224 GNDVIEDIKSVNLPTVQEWKSNIARYKASNISLGSVEQQQQQSIT 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(3)05822	NP_001262702.1	SH3	452..506	CDD:214620	16/55 (29%)
l(3)05822	NP_001262702.1	SH3	540..591	CDD:302595	4/25 (16%)
BEM1	NP_009759.3	SH3_Bem1p_1	76..127	CDD:212811	11/50 (22%)
		SH3_Bem1p_2	159..214	CDD:212812	17/54 (31%)
		PX_Bem1p	284..400	CDD:132800
		PB1	478..549	CDD:214770
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46655
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000