Protein Alignment l(3)05822 and Sh3d19

DIOPT Version :10

• Sequence 1: NP_652051.1
• Gene: l(3)05822 / 47260
• FlyBaseID: FBgn0010877
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: XP_006232845.1
• Gene: Sh3d19 / 295171
• RGDID: 1304885
• Length: 1071
• Species: Rattus norvegicus
• Alignment Length: 881
• Identity: 180/881 - (20%)
• Similarity: 276/881 - (31%)
• Gaps: 358/881 - (40%)

  Fly     4 PSRPA-----PAPPGSRGQSAAAGAN------------ASLEQLRLQLQQQHLQQ-QQGAGGGLQ 50
            |.|||     ..|||....|...|.:            .|.||:..::.|..:.. .........
  Rat    90 PLRPASWFPGAPPPGLGFPSTPVGGSWRPNDLVPAELPPSYEQVIKEINQVQVNSTNNNNAAATP 154

  Fly    51 KLTIKL-------------PPP----PKGPLQSQHKRTTVSNNNNG----SLFD----------- 83
            :.||..             |||    |..||||. ...:..|...|    .:||
  Rat   155 RSTITSATQTDFPEEIDGDPPPTLQAPLKPLQSS-PAASAGNLPPGVAPLIVFDICEEQNCPEKP 218

  Fly    84 --------EPTGGTSI----------TRKFPQARYTPATNWDDDPFGGGSNGNDRFKKMPPPRPP 130
                    .|...|::          .:..|::..||..:|
  Rat   219 SATRCPVPRPRSKTNLRPVARDAHSKEKNVPKSPVTPREDW------------------------ 259

  Fly   131 PPKVL------------VNGQNMTKSNSSMASAVTGGTGRLMSNI-------------FHRKKST 170
            ||:.|            :|..|..:|.:::.|.:....|:..:.|             ...|.:.
  Rat   260 PPQCLLDSTCNLDSQSVMNIMNTEQSQNTIISRIKAFEGQTSTEIPGPPKKPEIIPRTVPPKPAV 324

  Fly   171 STA------SAAASKAA------AENRVYGLSSGNAGATPSNNSSSSASSAAFSNVDWNAAWNTA 223
            |:.      ..||::|:      ||||:...|  ..|.|    |.||...|..:.|.........
  Rat   325 SSGKPLVAPKPAANRASGEWDSWAENRLKVTS--REGLT----SYSSPQEAGITPVTKPELPKKP 383

  Fly   224 TTTTTTTSSSSHSSHYASQQTADAQLISFDSPPSSPTFTQKSNS-----------DCVSVD---S 274
            |...|.|::...|......::.||.. ...:|...|...:||.|           ..|||.   |
  Rat   384 TPGLTRTANHETSGGRPMAESPDAGK-KIPTPAPRPLLPKKSASPDAPPYPSVPPKLVSVPPRLS 447

  Fly   275 FSSDSNF------SSPNNGSVSQPES---------GFEDDYHRSRPSTQSPLDPWEAVDSVGLGG 324
            .:|.:..      ..|:|..|..|:|         .|:||.   .|::.||.:
  Rat   448 VTSQAKAFRLPGEGPPSNPPVPAPQSKALGDIDLISFDDDV---LPTSGSPAE------------ 497

  Fly   325 VDSFGSAPVRQTYQVQSRGSDNPLCNGKSLLP-PTQSLTMPTIIKPKISQKP-----KAPKPPPF 383
             :..||..|...:|:.::   ......:::.| ||:.   ||:|  :|..||     :.|:.||.
  Rat   498 -EPIGSEMVLDPFQLPTK---TEATKERAVQPVPTRK---PTVI--RIPAKPGKCLHEEPQSPPP 553

  Fly   384 IGGHLPPG--YSIPSG-----------------YAGS------ETPPSP----------PMPKGP 413
            :....|.|  ||:.||                 .:||      ..||.|          |.|||.
  Rat   554 LPAEKPVGNTYSVASGRLSNSDRTRNPDLEQASESGSLVQGPPRLPPRPVHGKVIPVWRPPPKGA 618

  Fly   414 P--PPPPPAS----------------------------SG------------------------- 423
            |  ||||..|                            ||
  Rat   619 PERPPPPKLSATKSSNKNLPFNRSSSDMDLQRKPCHLASGLSKAKSQVFKNQDPVLPPRPKPGHP 683

  Fly   424 -----------GISLLDVINGKVDALALSNG---------------CQ----------------- 445
                       ||:..|:::.....|:...|               |:
  Rat   684 LYRKYMLSVPHGIANEDIVSQNPTELSCKRGDVLVILKQAENNYLECRRGEGTGRVHPSQMKIVT 748

  Fly   446 -------------GYMEEEV---VPYAVALYDFDGIEPGDLSFREGEKIYLLDHPTPEWLRGRTR 494
                         |:.::.|   .|:||||:||...:..|||...||.:|||:....||.||:.|
  Rat   749 PLDEHPRSRPNGSGHTQKPVDSGAPHAVALHDFPAEQADDLSLTSGEIVYLLEKIDAEWYRGKCR 813

  Fly   495 SGCEGIFPINYVD--IKVPLGATGGAAAAPTASAAAPSPSPSQQQLPTALCLYHFPGEVEGDLAL 557
            :. .||||.|||.  :.:|.|.:|...:..:..|..          ...:..:.:.|:.:.:|:.
  Rat   814 NQ-TGIFPANYVKVVVDIPEGRSGKRESFSSHCAKG----------QRCIARFEYIGDQKDELSF 867

  Fly   558 QENELVTVLYRINEDWLYGEVAGRQGQFPANFLDQV 593
            .|.|::.:...:||:|..||:..|.|.||.||::.|
  Rat   868 SEGEVIVLTGYVNEEWGRGEIRDRTGIFPLNFVELV 903

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(3)05822	NP_652051.1	SH3	452..506	CDD:214620	26/56 (46%)
		SH3	540..591	CDD:473055	15/50 (30%)
Sh3d19	XP_006232845.1	PHA03247	<307..684	CDD:223021	83/407 (20%)
		SH3	694..743	CDD:473055	6/48 (13%)
		SH3	774..825	CDD:473055	25/51 (49%)
		SH3_Eve1_3	850..900	CDD:212750	14/49 (29%)
		SH3	946..995	CDD:473055
		SH3_Eve1_5	1015..1064	CDD:212752