Protein Alignment l(3)05822 and Sh3d19

DIOPT Version :10

• Sequence 1: NP_652051.1
• Gene: l(3)05822 / 47260
• FlyBaseID: FBgn0010877
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: XP_011238437.1
• Gene: Sh3d19 / 27059
• MGIID: 1350923
• Length: 1071
• Species: Mus musculus
• Alignment Length: 859
• Identity: 184/859 - (21%)
• Similarity: 282/859 - (32%)
• Gaps: 314/859 - (36%)

  Fly     4 PSRPAP----APPGSRGQSAAAGAN-------------ASLEQLRLQLQQQHL---QQQQGAGGG 48
            |.|||.    |||...|..:..||.             .|.||:..::.|..:   .....|...
Mouse    96 PLRPASWFPGAPPPGLGFPSTPGAGPWRPNDLVPAELPPSYEQVIKEINQVQVNATNNNNAAATP 160

  Fly    49 LQKLT----------IKLPPPP--KGPLQSQHKRTTVSNNNNGS------LFD---EPT--GGTS 90
            ...:|          |...|||  :.||:........|..|...      :||   |.|  ...|
Mouse   161 RSTITSATQTDFPEDIDSDPPPTLQAPLKPLQPSPAASAGNLPPGVAPLIVFDICEEQTCPENPS 225

  Fly    91 ITRKFPQARYTPATNWDDDPFGGGSNGNDRFKKMPPPRP----PP-----------PKVLVNGQN 140
            .|| .|..|  |.:..:..|....:|..::..:..|..|    ||           .:.::|..|
Mouse   226 ATR-CPVPR--PRSKSNLRPVARDANSKEKNSQKSPVTPREDWPPHCLLDSTCNLDSQAMMNIMN 287

  Fly   141 MTKSNSSMASAVTGGTGRLMSNI-------------FHRKKSTSTA------SAAASKAA----- 181
            ..:|.:::.|.:....|:..:.|             ...|.:.|:.      ..||::|:
Mouse   288 TEQSQNTIVSRIKAFEGQTNTEIPGLPKKPEIIPRTIPPKPAVSSGKPLVAPKPAANRASGEWDT 352

  Fly   182 -AENRVYGLSSGNAGATPSNNSSSSASSAAFSNVDWNAAWNTATTTTTTTSSSSHSSHYASQQTA 245
             ||||:...|  ..|.||    .||...|..:.|.........|...|.:.:...|......::.
Mouse   353 WAENRLKVTS--REGLTP----YSSPQEAGITPVTKPELPKKPTPGLTRSVNHETSGGRPMAESP 411

  Fly   246 DA---------------QLISFDSPPSSPTFTQKSNSDCVSVDSFSSDSNFSS-----PNNGSVS 290
            |.               :..|.|:|| .|:...|..|....:...|....|.|     |:|..|.
Mouse   412 DTGKKIPTPAPRPLLPKKSASTDAPP-YPSIPPKLVSAPPRLSVASQAKAFRSLGEGLPSNPPVP 475

  Fly   291 QPES---------GFEDDYHRSRPSTQSPLDPWEAVDSVGLGGVDSFGSAPVRQTYQVQSRGSDN 346
            .|:|         .|:||.   .|::.||.:             :..||..|...:|:.::   .
Mouse   476 APQSKALGDIDLISFDDDV---LPTSGSPAE-------------EPTGSETVLDPFQLPTK---T 521

  Fly   347 PLCNGKSLLP-PTQSLTMPTIIKPKISQKP-----KAPKPPPFIGGHLPPG--YSIPSG------ 397
            .....:::.| ||:.   ||:|  :|..||     :.|:.||.:....|.|  :|..||
Mouse   522 EATKERAVQPAPTRK---PTVI--RIPAKPGKCLHEEPQSPPPLPAEKPVGNTHSAVSGRPSHSD 581

  Fly   398 -------YAGSET----------PPSP----------PMPKGPP--PPPP--PAS---------- 421
                   ...||:          ||.|          |.|||.|  ||||  |||
Mouse   582 RTRNPELEQASESGGLVQGPPRLPPRPVHGKVIPVWRPPPKGAPERPPPPKLPASKSSNKNLPFN 646

  Fly   422 ----------------SG------------------------------------GISLLDVINGK 434
                            ||                                    ||:..|:::..
Mouse   647 RSSSDMDLQKKQSHFVSGLSKAKSQIFKNQDPVLPPRPKPGHPLYRKYMLSVPHGIANEDIVSRN 711

  Fly   435 VDALALSNG---------------CQ------------------------------GYMEEEV-- 452
            ...|:...|               ||                              |:.::.|
Mouse   712 PTELSCKRGDVLVILKQAENNYLECQRGEGTGRVHPSQMKIVTPLDERPRGRPNDSGHSQKPVDS 776

  Fly   453 -VPYAVALYDFDGIEPGDLSFREGEKIYLLDHPTPEWLRGRTRSGCEGIFPINYVD--IKVPLGA 514
             .|:||||:||...:..|||...||.:|||:....||.||:.|:. .|:||.|||.  :.:|.|.
Mouse   777 GAPHAVALHDFPAEQADDLSLTSGEIVYLLEKIDAEWYRGKCRNQ-TGVFPANYVKVIVDIPEGR 840

  Fly   515 TGGAAAAPTASAAAPSPSPSQQQLPTALCLYHFPGEVEGDLALQENELVTVLYRINEDWLYGEVA 579
            :|...:..:..|..          |..:..:.:.|:.:.:|:..|.|::.:...:||:|..||:.
Mouse   841 SGKRESFSSHCAKG----------PRCVARFEYIGDQKDELSFSEGEVIILTEYVNEEWGRGEIR 895

  Fly   580 GRQGQFPANFLDQV 593
            .|.|.||.||::.|
Mouse   896 DRSGIFPLNFVELV 909

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(3)05822	NP_652051.1	SH3	452..506	CDD:214620	25/56 (45%)
		SH3	540..591	CDD:473055	15/50 (30%)
Sh3d19	XP_011238437.1	PHA03247	<103..624	CDD:223021	113/554 (20%)
		SH3_Eve1_1	700..749	CDD:212748	7/48 (15%)
		SH3	780..831	CDD:473055	24/51 (47%)
		SH3_Eve1_3	856..906	CDD:212750	14/49 (29%)
		SH3	946..995	CDD:473055
		SH3	1015..1064	CDD:473055