Protein Alignment dmGlut and SLC17A6

DIOPT Version :9

• Sequence 1: NP_620115.2
• Gene: dmGlut / 47253
• FlyBaseID: FBgn0010497
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_065079.1
• Gene: SLC17A6 / 57084
• HGNCID: 16703
• Length: 582
• Species: Homo sapiens
• Alignment Length: 499
• Identity: 162/499 - (32%)
• Similarity: 249/499 - (49%)
• Gaps: 47/499 - (9%)

  Fly    15 FVIPQRVILAIMGFLAILNAYTMRVCLSQAITVLVVKKNSTDDDSEAICEPDDIDEGTSV---GG 76
            |.:|:|.|:|||..|....::.:|..|..||..:|  .|||            |..|..|   ..
Human    65 FGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMV--NNST------------IHRGGKVIKEKA 115

  Fly    77 DFEWSEELQGLILSSFYIGYIVTHIPGGLLAEKFGGKWTLGLGILSTAVFTMLTPLA--INKGDS 139
            .|.|..|..|:|..||:.|||:|.||||.:|.:.......|..||.|:...||.|.|  ::.|
Human   116 KFNWDPETVGMIHGSFFWGYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYG-- 178

  Fly   140 DWLIVTRVLMGLGEGTTFPALSVLLAAWVPANERGKLGALVLGGGQVGTIMGNLLSGVFIDAYGW 204
             .:|..|:|.||.||.|:||...:.:.|.|..||.:|......|...|.::...|:|:.:...||
Human   179 -CVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGW 242

  Fly   205 EFVFYFFGGLGVVWFAIFMFLCYSDPTSHPFIKPSEREYLVKEIGTISRN----EDLPPTPWKAI 265
            ..|||.:|..|:||:..::.:.|..|..||.|...||.|:.:.||. |.|    .:...|||:..
Human   243 SSVFYVYGSFGMVWYMFWLLVSYESPAKHPTITDEERRYIEESIGE-SANLLGAMEKFKTPWRKF 306

  Fly   266 LTNLPMFALVAAQIGHDWGFYIMVTDLPKYMADVLQFSIKANGLYSSLPYVMMWIVSVGSGFVAD 330
            .|::|::|::.|.....|.||:::...|.|..:|..|.|...|:.|::|:::|.|:....|.:||
Human   307 FTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIAD 371

  Fly   331 WMIRRGVLSTTNTRKVMT--GLAAFGPAIFMVGASYAGCDRVLVVVLFTICMGLMGAYYAGMKLS 393
            ::..:.:||||..||:|.  |.......:.:||.|:.   |.:.:....:.:|..|...:|..::
Human   372 FLRSKQILSTTTVRKIMNCGGFGMEATLLLVVGYSHT---RGVAISFLVLAVGFSGFAISGFNVN 433

  Fly   394 PLDMSPNYAGTLMAITNGIGAITGVITPYLVGVMTPNASLLEWRLVFWVAFGVLCFTAVIYCIWA 458
            .||::|.||..||.|:||:|.::|::.|.:||.||.|.|..||:.||.:|..|.....:.|.|:|
Human   434 HLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKNKSREEWQYVFLIAALVHYGGVIFYAIFA 498

  Fly   459 SGEVQPFNNAPIQPRSVDFEAQERKVG-------GEKTSGLEQS 495
            |||.||:.:..        |..|.|.|       .|:|..:.|:
Human   499 SGEKQPWADPE--------ETSEEKCGFIHEDELDEETGDITQN 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dmGlut	NP_620115.2	2A0114euk	25..463	CDD:129972	148/448 (33%)
		MFS	77..458	CDD:119392	130/388 (34%)
SLC17A6	NP_065079.1	MFS_SLC17A6_7_8_VGluT	74..498	CDD:340940	145/444 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148709
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1866
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.770