Protein Alignment dmGlut and SLC17A7

DIOPT Version :9

• Sequence 1: NP_620115.2
• Gene: dmGlut / 47253
• FlyBaseID: FBgn0010497
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_064705.1
• Gene: SLC17A7 / 57030
• HGNCID: 16704
• Length: 560
• Species: Homo sapiens
• Alignment Length: 500
• Identity: 163/500 - (32%)
• Similarity: 255/500 - (51%)
• Gaps: 53/500 - (10%)

  Fly    15 FVIPQRVILAIMGFLAILNAYTMRVCLSQAITVLVVKKNSTDDDSEAICEPDDIDEGTSVGG--- 76
            |.:|:|.|:|||..|....::.:|..|..||..:|  .|||                |..||
Human    57 FGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMV--NNST----------------THRGGHVV 103

  Fly    77 ----DFEWSEELQGLILSSFYIGYIVTHIPGGLLAEKFGGKWTLGLGILSTAVFTMLTPLA--IN 135
                .|.|..|..|||..||:.|||||.||||.:.:||......|..|::|:...||.|.|  ::
Human   104 VQKAQFSWDPETVGLIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAIVATSTLNMLIPSAARVH 168

  Fly   136 KGDSDWLIVTRVLMGLGEGTTFPALSVLLAAWVPANERGKLGALVLGGGQVGTIMGNLLSGVFID 200
            .|   .:|..|:|.||.||.|:||...:.:.|.|..||.:|......|...|.::...|:||.:.
Human   169 YG---CVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQ 230

  Fly   201 AYGWEFVFYFFGGLGVVWFAIFMFLCYSDPTSHPFIKPSEREYLVKEIGTISRNEDLPP-----T 260
            ..||..|||.:|..|:.|:..::.:.|..|..||.|...||:|:...||..::.  :.|     |
Human   231 YSGWSSVFYVYGSFGIFWYLFWLLVSYESPALHPSISEEERKYIEDAIGESAKL--MNPLTKFST 293

  Fly   261 PWKAILTNLPMFALVAAQIGHDWGFYIMVTDLPKYMADVLQFSIKANGLYSSLPYVMMWIVSVGS 325
            ||:...|::|::|::.|.....|.||:::...|.|..:|..|.|...||.|:||:::|.|:....
Human   294 PWRRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLVSALPHLVMTIIVPIG 358

  Fly   326 GFVADWMIRRGVLSTTNTRKVMT--GLAAFGPAIFMVGASYAGCDRVLVVVLFTICMGLMGAYYA 388
            |.:||::..|.::||||.||:|.  |.......:.:||.|::   :.:.:....:.:|..|...:
Human   359 GQIADFLRSRRIMSTTNVRKLMNCGGFGMEATLLLVVGYSHS---KGVAISFLVLAVGFSGFAIS 420

  Fly   389 GMKLSPLDMSPNYAGTLMAITNGIGAITGVITPYLVGVMTPNASLLEWRLVFWVAFGVLCFTAVI 453
            |..::.||::|.||..||.|:||:|.::|::.|.:||.||.:.:..||:.||.:|..|.....:.
Human   421 GFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKHKTREEWQYVFLIASLVHYGGVIF 485

  Fly   454 YCIWASGEVQPFNNAPIQPRSVDFEAQERK---VGGEKTSGLEQS 495
            |.::||||.||:    .:|.    |..|.|   ||.::.:|.:.|
Human   486 YGVFASGEKQPW----AEPE----EMSEEKCGFVGHDQLAGSDDS 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dmGlut	NP_620115.2	2A0114euk	25..463	CDD:129972	148/453 (33%)
		MFS	77..458	CDD:119392	130/389 (33%)
SLC17A7	NP_064705.1	MFS_SLC17A6_7_8_VGluT	66..490	CDD:340940	145/449 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	497..560		7/33 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148581
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1866
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.770