DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dmGlut and Slc37a1

DIOPT Version :9

Sequence 1:	NP_620115.2	Gene:	dmGlut / 47253	FlyBaseID:	FBgn0010497	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_001011944.1	Gene:	Slc37a1 / 294321	RGDID:	1308587	Length:	537	Species:	Rattus norvegicus

Alignment Length:	544	Identity:	114/544 - (20%)
Similarity:	210/544 - (38%)	Gaps:	137/544 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ISLSR---YFVIPQRVILAIMGFLAILNAYTMRVCLSQAITVLVVKKNSTDDDSEAICEPDD--- 67
            ||.||   |     |..:.::.||...:.:..|..:|       :.|........|..||:.
  Rat    12 ISFSRDQWY-----RAFIFMLTFLLYASFHLSRKPIS-------IVKGELHKQCAAADEPEPRFG 64

  Fly    68 --------------IDEGTSVGGDFEWS-------EELQGLILSSFYIGYIVTHIPGGLLAEKFG 111
                          ::..|....|..|:       ::|.|.:..:|...|.:.....|::.|:..
  Rat    65 GPSSSTRRSPTHWLLNNETETETDCGWAPFDKNNYQQLLGALDYAFLCAYAIGMYLSGIIGERLP 129

  Fly   112 GKWTLGLGILSTAVFTMLTPLA--INKGDSDWLIVTRVLMGLGEGTTFPALSVLLAAWVPANERG 174
            .::.|..|:|::..||.|..|.  .|.....:.:||:::.||.:.|.:|::...|:.|.....||
  Rat   130 IRYYLTFGMLASGAFTALFGLGYFYNIHSLGFYVVTQIINGLVQTTGWPSVVTCLSNWFGKGRRG 194

  Fly   175 KLGALVLGGGQVGTIMGNLLSGVFID-AYGWEFVF--YFFGGLGVVWFAIFMFL--------CYS 228
            .:..:......||.|:|:|::|.::. .:|..|:.  ...|.:|:|   .|:||        |.|
  Rat   195 LIMGIWNSHTSVGNILGSLIAGYWVSTCWGLSFIVPGAIVGAMGIV---CFLFLIEHPKDIKCSS 256

  Fly   229 DPTSHPFIKPSE----REYLVKEIGTISRNEDLPPTPWKAILTN------------LP------- 270
            ...:||  :.||    |..:.|:.....:|..|.|.....:|::            ||
  Rat   257 TLPTHP--RASENGINRFRVQKQTTHSEKNGPLDPELQCLLLSDGKSPLHPSHIVVLPGDRTSSM 319

  Fly   271 ------------------MFALVAAQIGHDWGFYIMVTDLPKYMADVLQFSIKANGLYSSLPYVM 317
                              :..|.|..:.:.:.|:     ||.|:.:|.....|..|..|:|..|.
  Rat   320 AAISFTGALRIPGVIEFSLCLLFAKLVSYTFLFW-----LPLYITNVDHLDAKKAGELSTLFDVG 379

  Fly   318 MWIVSVGSGFVADWMIRRGVLSTTNTRKVMTGLAAFGPAIFMVGA-SYAGCDRVLVVVLFTICMG 381
            .....:.:|.::|.:.:|     .:|..:|..|||  |.:::..: |..|.:..:.::|
  Rat   380 GIFGGILAGVISDRLEKR-----ASTCGLMLLLAA--PTLYVFSSVSKMGLEATIAMLL------ 431

  Fly   382 LMGAYYAGMKL-------------SPLDMSPNYAGTLMAITNGIGAITGVITPYLVGVMTPNASL 433
            |.||..:|...             ..|..:.:...|:.||.:|.|::...:.|.|.|:::|:.
  Rat   432 LSGALVSGPYALITTAVSADLGTHKSLKGNSHALSTVTAIIDGTGSVGAALGPLLAGLISPSG-- 494

  Fly   434 LEWRLVFW-VAFGVLCFTAVIYCI 456
              |..||: :.|...|  |:::.|
  Rat   495 --WSNVFYMLMFADAC--ALLFLI 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dmGlut	NP_620115.2	2A0114euk	25..463	CDD:129972	108/525 (21%)
dmGlut	NP_620115.2	MFS	77..458	CDD:119392	99/456 (22%)
Slc37a1	NP_001011944.1	MFS_SLC37A1_2	21..520	CDD:340902	109/530 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342600
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840