DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dmGlut and SPAC11D3.18c

DIOPT Version :9

Sequence 1:	NP_620115.2	Gene:	dmGlut / 47253	FlyBaseID:	FBgn0010497	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_001342807.1	Gene:	SPAC11D3.18c / 2543005	PomBaseID:	SPAC11D3.18c	Length:	498	Species:	Schizosaccharomyces pombe

Alignment Length:	495	Identity:	102/495 - (20%)
Similarity:	181/495 - (36%)	Gaps:	121/495 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 VILAIMGFLAILNAYTMRVCLSQAITVLVVKKNSTDDDSEAICEPDDIDEGTSVGGDFEWSEELQ 85
            ||..|:|||.:: |:..|..:..|...                   .:.|..|:.|      |..
pombe    60 VISPIIGFLYLM-AFLDRSNIGNAAVA-------------------GMTEALSLYG------ERL 98

  Fly    86 GLILSSFYIGYIVTHIPGGLLAEKFGGKWTLGLGILSTAVFTMLTPLAINKGDSDWLIVTRVLMG 150
            .:.:|.||:.||:...|..:|.::......|.....:.::..:.:....:.|.   ||.||:::|
pombe    99 NVAVSIFYVLYILVETPSVVLVKRIKASRMLAFISFAWSMTVLFSGFMSSYGG---LIATRLILG 160

  Fly   151 LGEGTTFPALSVLLAAWVPANER-GKLGALVLGGGQVGTIMGNLLSGVFIDAY-----------G 203
            |.||..||||::.|.......|: .:|..|....|..|.     ..|:|  ||           |
pombe   161 LLEGCLFPALNLYLTTHYTRKEQCQRLSYLFASAGLAGA-----FGGLF--AYALEQVHAGNKEG 218

  Fly   204 WEFVFYFFGGLGVVWFAIFMFLCYSDPTSHPFIKPSEREYLVKEIGTISRNEDLPPTPWKAI--- 265
            |::::...|.:..:...:.:|.......:..|:...|||..:......:|........|..:
pombe   219 WQWIYIVEGLVSFIGVPLCLFALPDKMENAWFLTREEREVAIIRRDINARYHGEQHFEWSEVRKA 283

  Fly   266 LTNLPMFALVAAQIGHDWGFYIMVTDLPKYMADVLQFSIKANGLYSSLPYVMMWIVSVGSGFVAD 330
            ..:..::....:|...|...|...:.||..:..:....::.|  |.::|..:..::|.  .|||
pombe   284 FKDPKVYVSATSQFCADMVLYGFSSFLPVIIKGLGFVGLQTN--YMTIPVYIAGVISF--LFVA- 343

  Fly   331 WMIRRGVLSTTNTRKVMTGLAAFGPAIFMVGASYAGCDRVLVVVLFTICMG-------------- 381
            |:..|     |..|           |::::.||      .:|.|.:.|.:.
pombe   344 WLSDR-----TQLR-----------AVYLISAS------TVVAVGYIIMLASDSNAAKYTATYII 386

  Fly   382 LMGAYYA-GMKLSPL--DMSPNY-----AGTLMAITNGIGAITGVI------TPYLVGVMTPNAS 432
            .:|.|.. |:.|..|  :::.:|     .|....:.|..|.:.|.|      ..|::|    ||.
pombe   387 AIGCYIGPGLNLGWLNNNVAGHYKRATAIGIQQTLANSSGIVAGQIYRSKNAPKYILG----NAF 447

  Fly   433 LLEWRLVFWVAFGVLCFTAVIY--------CIWASGEVQP 464
            .|...:|..:|: |:.|.::.|        |  |.||..|
pombe   448 TLGCVIVGGLAY-VVMFFSLRYVNKKRDERC--ARGEFDP 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dmGlut	NP_620115.2	2A0114euk	25..463	CDD:129972	99/488 (20%)
dmGlut	NP_620115.2	MFS	77..458	CDD:119392	86/431 (20%)
SPAC11D3.18c	NP_001342807.1	UhpC	68..461	CDD:332119	89/460 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050