Protein Alignment dmGlut and SLC37A4

DIOPT Version :10

• Sequence 1: NP_620115.2
• Gene: dmGlut / 47253
• FlyBaseID: FBgn0010497
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001157750.1
• Gene: SLC37A4 / 2542
• HGNCID: 4061
• Length: 451
• Species: Homo sapiens
• Alignment Length: 445
• Identity: 92/445 - (20%)
• Similarity: 164/445 - (36%)
• Gaps: 132/445 - (29%)

  Fly    86 GLILSSFYIGYIVTHIPGGLLAEKFGGKWTLGLGIL-------------STAVFTMLTPLAINKG 137
            |.|.||....|.::....|:|:::...:|....|:|             :..||..|
Human    50 GFITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNIFFAWSSTVPVFAAL-------- 106

  Fly   138 DSDWLIVTRVLMGLGEGTTFPALSVLLAAWVPANERGKLGALV-----LGGGQVGTIMGNLLSGV 197
               |.     |.||.:|..:|....:|..|...::.|...|::     |.||     :|.:|:.:
Human   107 ---WF-----LNGLAQGLGWPPCGKVLRKWFEPSQFGTWWAILSTSMNLAGG-----LGPILATI 158

  Fly   198 FIDAYGWEFVFYFFGGLGVVWFAIFMFLCYSDPTS------HPFIKPSE-REYLVKEIGTISRNE 255
            ...:|.|.......|.|.||...:.:.|.:::|..      .|.  ||| ::..:||..|:   :
Human   159 LAQSYSWRSTLALSGALCVVVSFLCLLLIHNEPADVGLRNLDPM--PSEGKKGSLKEESTL---Q 218

  Fly   256 DLPPTPWKAILTNLPMFALVAAQIGHDWGFYIMVTDL-------PKYMADVLQFSIKANGLYSSL 313
            :|..:|:..:|:...:..........|||.:.::.:.       ..||:     :::..||
Human   219 ELLLSPYLWVLSTGYLVVFGVKTCCTDWGQFFLIQEKGQSALVGSSYMS-----ALEVGGL---- 274

  Fly   314 PYVMMWIVSVGSGFVAD-WMIRRGVLSTTNTRKVMTGLAAFGPAIFMVGASYAGCD------RVL 371
                  :.|:.:|:::| .|.:.|:.:..|.|        .|..:||:    ||..      ||.
Human   275 ------VGSIAAGYLSDRAMAKAGLSNYGNPR--------HGLLLFMM----AGMTVSMYLFRVT 321

  Fly   372 V-------VVLFTICMG----------------LMGAYYAGMKLSPLDM---------SPNYAGT 404
            |       |..:|:.:.                ::||.:......|:.:         .||..||
Human   322 VTSDSPKDVAFWTLALHPLAELTGFTEHELWILVLGAVFGFSSYGPIALFGVIANESAPPNLCGT 386

  Fly   405 LMAITNGIGAITGVITPYLVGV-MTPNASLLEWRLVFWVAFGVLC--FTAVIYCI 456
            ..||...:..:.|    :|.|: .:..|....|...|||| .|:|  .||..:.:
Human   387 SHAIVGLMANVGG----FLAGLPFSTIAKHYSWSTAFWVA-EVICAASTAAFFLL 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dmGlut	NP_620115.2	MFS_SLC17	24..458	CDD:340876	92/445 (21%)
SLC37A4	NP_001157750.1	MFS_SLC37A4	10..439	CDD:340901	92/445 (21%)