Protein Alignment dmGlut and SLC37A4

DIOPT Version :9

• Sequence 1: NP_620115.2
• Gene: dmGlut / 47253
• FlyBaseID: FBgn0010497
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001157750.1
• Gene: SLC37A4 / 2542
• HGNCID: 4061
• Length: 451
• Species: Homo sapiens
• Alignment Length: 445
• Identity: 92/445 - (20%)
• Similarity: 164/445 - (36%)
• Gaps: 132/445 - (29%)

  Fly    86 GLILSSFYIGYIVTHIPGGLLAEKFGGKWTLGLGIL-------------STAVFTMLTPLAINKG 137
            |.|.||....|.::....|:|:::...:|....|:|             :..||..|
Human    50 GFITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNIFFAWSSTVPVFAAL-------- 106

  Fly   138 DSDWLIVTRVLMGLGEGTTFPALSVLLAAWVPANERGKLGALV-----LGGGQVGTIMGNLLSGV 197
               |.     |.||.:|..:|....:|..|...::.|...|::     |.||     :|.:|:.:
Human   107 ---WF-----LNGLAQGLGWPPCGKVLRKWFEPSQFGTWWAILSTSMNLAGG-----LGPILATI 158

  Fly   198 FIDAYGWEFVFYFFGGLGVVWFAIFMFLCYSDPTS------HPFIKPSE-REYLVKEIGTISRNE 255
            ...:|.|.......|.|.||...:.:.|.:::|..      .|.  ||| ::..:||..|:   :
Human   159 LAQSYSWRSTLALSGALCVVVSFLCLLLIHNEPADVGLRNLDPM--PSEGKKGSLKEESTL---Q 218

  Fly   256 DLPPTPWKAILTNLPMFALVAAQIGHDWGFYIMVTDL-------PKYMADVLQFSIKANGLYSSL 313
            :|..:|:..:|:...:..........|||.:.::.:.       ..||:     :::..||
Human   219 ELLLSPYLWVLSTGYLVVFGVKTCCTDWGQFFLIQEKGQSALVGSSYMS-----ALEVGGL---- 274

  Fly   314 PYVMMWIVSVGSGFVAD-WMIRRGVLSTTNTRKVMTGLAAFGPAIFMVGASYAGCD------RVL 371
                  :.|:.:|:::| .|.:.|:.:..|.|        .|..:||:    ||..      ||.
Human   275 ------VGSIAAGYLSDRAMAKAGLSNYGNPR--------HGLLLFMM----AGMTVSMYLFRVT 321

  Fly   372 V-------VVLFTICMG----------------LMGAYYAGMKLSPLDM---------SPNYAGT 404
            |       |..:|:.:.                ::||.:......|:.:         .||..||
Human   322 VTSDSPKDVAFWTLALHPLAELTGFTEHELWILVLGAVFGFSSYGPIALFGVIANESAPPNLCGT 386

  Fly   405 LMAITNGIGAITGVITPYLVGV-MTPNASLLEWRLVFWVAFGVLC--FTAVIYCI 456
            ..||...:..:.|    :|.|: .:..|....|...|||| .|:|  .||..:.:
Human   387 SHAIVGLMANVGG----FLAGLPFSTIAKHYSWSTAFWVA-EVICAASTAAFFLL 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dmGlut	NP_620115.2	2A0114euk	25..463	CDD:129972	92/445 (21%)
		MFS	77..458	CDD:119392	92/445 (21%)
SLC37A4	NP_001157750.1	MFS	14..437	CDD:119392	92/445 (21%)
		2A0104	18..419	CDD:273319	84/425 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148707
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840