DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dmGlut and liz1

DIOPT Version :9

Sequence 1:	NP_620115.2	Gene:	dmGlut / 47253	FlyBaseID:	FBgn0010497	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_001342731.1	Gene:	liz1 / 2540342	PomBaseID:	SPBC2G2.01c	Length:	514	Species:	Schizosaccharomyces pombe

Alignment Length:	487	Identity:	100/487 - (20%)
Similarity:	174/487 - (35%)	Gaps:	118/487 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 TQQPQWGISLSRYFVIPQRVILAIMGFLAILNAYTMRVCLSQAITVLVVKKNSTDDDSEAICEPD 66
            |..|.:|::     .:.|::::.|..|:.   :|   .|:|..|       |..|..|.......
pombe    10 TFSPYYGLN-----KVEQKLLIKIDWFIL---SY---CCVSYFI-------NYLDRSSINNAYLS 56

  Fly    67 DIDEGTSVGGDFEWSEELQGLILSSFYIGYIVTHIPGGLLAEKFGGK---------WTLGLGILS 122
            .:.|...:.|:     |||.:.: .|..|||:..:||....::...:         |.| :.|.|
pombe    57 GMQEDLKMHGN-----ELQDINV-VFTCGYIIGQLPGSYALQRVPARLWFSVMNILWGL-MTIFS 114

  Fly   123 TAVFTMLTPLAINKGDSDWLIVTRVLMGLGEGTTFPALSVLLAAWVPANERGKLGALVLGGGQVG 187
            .||.::..           |::.|..|.:.|.:||.....:|.||...:|..|...:....|.||
pombe   115 FAVHSVRA-----------LMILRFFMAVAEASTFAGTHYILGAWYKESELCKRAGIFSASGLVG 168

  Fly   188 TIMGNLLSGVFIDAY-------GWEFVFYFFGGLGV--VWFAIFMFLCYSDPTSHPFIKPSEREY 243
            |:....|......:.       ||.::|...|.|.:  ..:.:|:|....:.|..|:....|:|.
pombe   169 TMFAGYLQTAVHSSLNGKGGLSGWRWLFIIDGILTIPLSLYGLFLFPDVPETTKAPYFTEQEKEL 233

  Fly   244 LVKEIGTISRNEDLPPTPWKAILTNLPMFALVAAQIGHDWGFY------IMVTDLPKYMADVL-- 300
            ..|.         ||..|.|.     |:.......|...|..|      |...:......:||
pombe   234 SFKR---------LPARPKKK-----PLTLKAIKDIVRSWRIYGLCILWIFSGETQAIAVNVLMG 284

  Fly   301 -------QFSIKANGLYSSLPYVMMWIVSVGSGFVAD-------WMIRRGVLSTTNTRKVMTGLA 351
                   :||:.....|.::...:..:.::|:..::|       |..  |:.....|....|.|.
pombe   285 QWMKWSNKFSVAQINNYPTVITAVGVVSTLGASVISDKLAGNPRWPF--GLFLCVITTVSATILL 347

  Fly   352 AFGP-------AIFMVGASYAG-----------C-----DRVLVVVLFTICMGLMGAYYAGMKLS 393
            |:..       |.|..|.:|||           |     :|.:||.|..:|..:...::|.: :.
pombe   348 AWNVPDGAKFFAYFASGCTYAGQAVWFSWANDICRDNDQERGVVVFLMNMCQNIWHIWWAPI-MY 411

  Fly   394 PLDMSPNYAGTL--MAITNGIGAITGVITPYL 423
            |...:|.:...|  :.:..||..::..|..|:
pombe   412 PNTDTPRFIKGLIGLLVVGGIVFVSSCIVSYM 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dmGlut	NP_620115.2	2A0114euk	25..463	CDD:129972	96/464 (21%)
dmGlut	NP_620115.2	MFS	77..458	CDD:119392	85/412 (21%)
liz1	NP_001342731.1	MFS_1	37..401	CDD:311564	85/404 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050