DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dmGlut and SPCC417.10

DIOPT Version :9

Sequence 1:	NP_620115.2	Gene:	dmGlut / 47253	FlyBaseID:	FBgn0010497	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_588287.1	Gene:	SPCC417.10 / 2539419	PomBaseID:	SPCC417.10	Length:	508	Species:	Schizosaccharomyces pombe

Alignment Length:	488	Identity:	105/488 - (21%)
Similarity:	186/488 - (38%)	Gaps:	104/488 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 VCLSQAITVLVVKKNSTDDDSEAICEPDDIDEGTSVGGD-FEWSEELQGLILSSFYIGYIVTHIP 102
            :||...|..|       |..|.:......:.|...:.|. :.||.       ::||:||:|...|
pombe    69 MCLVYCIQFL-------DKTSNSYAVIMGLKEDLKMEGQMYSWSG-------TAFYLGYLVFEFP 119

  Fly   103 GGLLAEKFGGKWTLGLGILSTAVFTMLTPLAINKGDSDWLIVTRVLMGLGEGTTFPALSVLLAAW 167
            ..||.::|....||.:.::.......:|.:|...|    .|..|||:|:.|....|...:|.|.|
pombe   120 ASLLLQRFPLSKTLCVFLVIWGFLLCMTSVANYPG----FIALRVLLGMMESAASPGFILLTAQW 180

  Fly   168 VPANERGKLGALVLGGGQVGTIMGN-----LLSGVFIDAYGWEFVFYFFGGLGVVWFAIFMFLCY 227
            ...:|:....::.:....:|.|:|:     |.....:...||:.:|...|.|.:....:.:.:..
pombe   181 YKRSEQQLRTSVWVAFNGLGQILGSCMAYGLAKRTSLPMRGWKLIFIICGVLAIFLGFVILAVVP 245

  Fly   228 SDPTSHPFIKPSEREYLVKEIGT----ISRNE---------DLPPTPW----KAILTNLP----- 270
            .:|....|:...:|:.:||.:..    :..|.         .|....|    .::|.|:|
pombe   246 DNPFKAWFLTEEDRKLVVKRLRANKQGVGNNHFKLYQFKETMLDIRTWIMFVSSVLLNIPNGGIG 310

  Fly   271 MFA--LVAAQIGHDWGFYIMVTDLPKYMADVLQFSIKANGLYSSLPYVMMWIVSVGSGFVADWMI 333
            .|:  |:...:|:| ....::..||   |...:|    .||             :..||::.::.
pombe   311 TFSSLLIKGTMGYD-TLQTLLMGLP---AGACEF----GGL-------------IAFGFLSLFIH 354

  Fly   334 RRGVLSTTNTRKVMTGLAAFGPAIFMVGASYAGCDRVLVV--VLFTICMGLMGAYYAGMKLSPLD 396
            :|.||:|     :.|.:|..|..:.    |:||..|..:.  .|..:..|.|...:|       .
pombe   355 KRMVLAT-----ITTCIALIGSCLL----SFAGPPRAQLAGYYLLMVSPGAMIVMFA-------I 403

  Fly   397 MSPNYAGTLMAITNGIGAITGVITPYLVGVMT------PNASLLEWRLVFWVAFGVLCFTAVIYC 455
            :|.|.:|....:|.|:..:.|.....|:|..|      |.....:..:|...|..::.|.|:.|.
pombe   404 ISSNASGYTKKVTVGVIYLIGYCVGNLIGPQTFKAADAPEYMPAKNTMVGCYAATLVTFPALYYV 468

  Fly   456 IW----------ASGEVQPFNNAPIQPRSVDFE 478
            .|          |.|:::...||..:..: |||
pombe   469 NWRENKRRDQLAAEGKIEHRPNAEFEDLT-DFE 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dmGlut	NP_620115.2	2A0114euk	25..463	CDD:129972	100/471 (21%)
dmGlut	NP_620115.2	MFS	77..458	CDD:119392	90/428 (21%)
SPCC417.10	NP_588287.1	MFS	66..436	CDD:119392	90/421 (21%)
SPCC417.10	NP_588287.1	2A0114	71..468	CDD:273326	95/451 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
TreeFam	0	0.000	Not matched by this tool.
	5	4.960