DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dmGlut and Slc37a1

DIOPT Version :9

Sequence 1:	NP_620115.2	Gene:	dmGlut / 47253	FlyBaseID:	FBgn0010497	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_001229356.1	Gene:	Slc37a1 / 224674	MGIID:	2446181	Length:	531	Species:	Mus musculus

Alignment Length:	454	Identity:	98/454 - (21%)
Similarity:	183/454 - (40%)	Gaps:	103/454 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 DFEWS-------EELQGLILSSFYIGYIVTHIPGGLLAEKFGGKWTLGLGILSTAVFTMLTPLA- 133
            |..|:       ::|.|.:..:|...|.:.....|::.|:...::.|..|:|::..||.|..|.
Mouse    84 DCGWAPFDKNNYQQLLGALDYAFLCAYAIGMYLSGIIGERLPIRYYLTFGMLASGAFTALFGLGY 148

  Fly   134 -INKGDSDWLIVTRVLMGLGEGTTFPALSVLLAAWVPANERGKLGALVLGGGQVGTIMGNLLSGV 197
             .|.....:.:||:::.||.:.|.:|::...|:.|.....||.:..:......||.|:|:|::|.
Mouse   149 FYNIHSLGFYVVTQIINGLVQTTGWPSVVTCLSNWFGKGRRGLIMGIWNSHTSVGNILGSLIAGY 213

  Fly   198 FID-AYGWEFVF--YFFGGLGVVWFAIFMFL--------CYSDPTSHPFIKPSE----REYLVKE 247
            ::. .:|..|:.  .....:|:|   .|:||        |.|...:||  :.||    |..|.|:
Mouse   214 WVSTCWGLSFIVPGAIVAAMGIV---CFLFLIEHPKDVKCSSTLPTHP--RASENGINRFRLQKQ 273

  Fly   248 IGTISRNEDLPPTPWKAILTN------------LP-----------------------MFALVAA 277
            .....:|..|.|.....:|::            ||                       :..|.|.
Mouse   274 TTYSEKNGPLDPELQCLLLSDGKNPLHPSHIVVLPADGNMAAISFTGALRIPGVIEFSLCLLFAK 338

  Fly   278 QIGHDWGFYIMVTDLPKYMADVLQFSIKANGLYSSLPYVMMWIVSVGSGFVADWMIRRGVLSTTN 342
            .:.:.:.|:     ||.|:..|.....|..|..|:|..|......:.:|.::|.:.:|     .:
Mouse   339 LVSYTFLFW-----LPLYITSVDHLDAKKAGELSTLFDVGGIFGGILAGVISDRLEKR-----AS 393

  Fly   343 TRKVMTGLAAFGPAIFMVGA-SYAGCDRVLVVVLFTICMGLMGAYYAGMKL-------------S 393
            |..:|..|||  |.:::..: |..|.:..:.::|      |.||..:|...             .
Mouse   394 TCGLMLLLAA--PTLYVFSSVSRMGLEATIAMLL------LSGALVSGPYALITTAVSADLGTHK 450

  Fly   394 PLDMSPNYAGTLMAITNGIGAITGVITPYLVGVMTPNASLLEWRLVFW-VAFGVLCFTAVIYCI 456
            .|..:.:...|:.||.:|.|::...:.|.|.|:::|:.    |..||: :.|...|  |:::.:
Mouse   451 SLKGNSHALSTVTAIIDGTGSVGAALGPLLAGLISPSG----WSNVFYMLMFADAC--ALLFLV 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dmGlut	NP_620115.2	2A0114euk	25..463	CDD:129972	98/454 (22%)
dmGlut	NP_620115.2	MFS	77..458	CDD:119392	98/454 (22%)
Slc37a1	NP_001229356.1	MFS_SLC37A1_2	21..514	CDD:340902	98/454 (22%)
Slc37a1	NP_001229356.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	53..72
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838793
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840