Protein Alignment dmGlut and SLC37A2

DIOPT Version :10

• Sequence 1: NP_620115.2
• Gene: dmGlut / 47253
• FlyBaseID: FBgn0010497
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_938018.1
• Gene: SLC37A2 / 219855
• HGNCID: 20644
• Length: 505
• Species: Homo sapiens
• Alignment Length: 494
• Identity: 119/494 - (24%)
• Similarity: 204/494 - (41%)
• Gaps: 95/494 - (19%)

  Fly    20 RVILAIMGFLAILNAYTMRVCLSQAITVLVVKKNSTDDDSEAICEPDDIDEGTSVGGDFEWS--- 81
            |.::.::.||.....:..|..:|      :||.....:.||.|...:|    |....|..|.
Human    22 RGLILLLTFLIYACYHMSRKPIS------IVKSRLHQNCSEQIKPIND----THSLNDTMWCSWA 76

  Fly    82 -------EELQGLILSSFYIGYIVTHIPGGLLAEKFGGKWTLGLGILSTAVFTMLTPLAI--NKG 137
                   :||.|.:.::|.|.|.:.....|:..|:...::.|..|:|.:.:||.|..|..  |..
Human    77 PFDKDNYKELLGGVDNAFLIAYAIGMFISGVFGERLPLRYYLSAGMLLSGLFTSLFGLGYFWNIH 141

  Fly   138 DSDWLIVTRVLMGLGEGTTFPALSVLLAAWVPANERGKLGALVLGGGQVGTIMGNLLSGVFIDAY 202
            :..:.:|.:|..||.:.|.:|::...:..|....:||.:..:......||.|:|:|::|::::..
Human   142 ELWYFVVIQVCNGLVQTTGWPSVVTCVGNWFGKGKRGFIMGIWNSHTSVGNILGSLIAGIWVNGQ 206

  Fly   203 GWEFVFYFFGGLGVVWFAI-FMFL--------CYSDPTSHPFIKPSERE----------YLVKEI 248
             |...|...|.:..|...| |:||        | :.|..|.  :|:|.:          ..::|.
Human   207 -WGLSFIVPGIITAVMGVITFLFLIEHPEDVDC-APPQHHG--EPAENQDNPEDPGNSPCSIRES 267

  Fly   249 G--TISRNEDLPPTPWKAI----------LTNLPMFALVAAQIGHDWGFYIMVTDLPKYMADVLQ 301
            |  |:::....|.....||          :....:..|.|..:.:.:.::     ||.|:|:|..
Human   268 GLETVAKCSKGPCEEPAAISFFGALRIPGVVEFSLCLLFAKLVSYTFLYW-----LPLYIANVAH 327

  Fly   302 FSIKANGLYSSLPYVMMWIVSVGSGFVADWMIRRGVLSTTNTRK----VMTGLAAFGPAIFMVGA 362
            ||.|..|..|:|..|...|..:.:|.|:|:         ||.|.    ||..|||  |.:|:.
Human   328 FSAKEAGDLSTLFDVGGIIGGIVAGLVSDY---------TNGRATTCCVMLILAA--PMMFLY-- 379

  Fly   363 SYAGCDRVL-VVVLFTICMGLMGAYYA----------GMKLSPLDMSPNYAGTLMAITNGIGAIT 416
            :|.|.|.:. .:|:..||.||:...||          |...| |..:.....|:.||.:|.|:|.
Human   380 NYIGQDGIASSIVMLIICGGLVNGPYALITTAVSADLGTHKS-LKGNAKALSTVTAIIDGTGSIG 443

  Fly   417 GVITPYLVGVMTPNASLLEWRLVFWVAFGVLCFTAVIYC 455
            ..:.|.|.|:::|..    |..||::.........::.|
Human   444 AALGPLLAGLISPTG----WNNVFYMLISADVLACLLLC 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dmGlut	NP_620115.2	MFS_SLC17	24..458	CDD:340876	118/490 (24%)
SLC37A2	NP_938018.1	MFS_SLC37A1_2	22..484	CDD:340902	119/494 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..262		4/23 (17%)