Protein Alignment dmGlut and SLC17A3

DIOPT Version :9

• Sequence 1: NP_620115.2
• Gene: dmGlut / 47253
• FlyBaseID: FBgn0010497
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001091956.1
• Gene: SLC17A3 / 10786
• HGNCID: 10931
• Length: 498
• Species: Homo sapiens
• Alignment Length: 487
• Identity: 143/487 - (29%)
• Similarity: 248/487 - (50%)
• Gaps: 37/487 - (7%)

  Fly     6 QWGISLSRYF----VIPQRVILAIMGFLAILNAYTMRVCLSQAITVLVVKKNSTDDDSEAICEPD 66
            ::||:|..:|    .|.|.||:.|. .:|::|:.:.:..|:.:..||.|  :|....|:|   |.
Human    38 RYGIALVLHFCNFTTIAQNVIMNIT-MVAMVNSTSPQSQLNDSSEVLPV--DSFGGLSKA---PK 96

  Fly    67 DIDEGTSVGGDFEWSEELQGLILSSFYIGYIVTHIPGGLLAEKFGGKWTLGLGILSTAVFTMLTP 131
            .:.....|   ::||.::||:|..:...|.|:|..|.|.||.:.|.|..:|:.:.:|:..|:..|
Human    97 SLPAKAPV---YDWSPQIQGIIFGAVGYGGILTMAPSGYLAGRVGTKRVVGISLFATSFLTLCIP 158

  Fly   132 LAINKGDSDWLIVTRVLMGLGEGTTFPALSVLLAAWVPANERGKLGALVLGGGQVGTIMGNLLSG 196
            ||.:.| ...|||||::.||.:.:.......:...|.|..||.:|.::.|.|..:|.....|:.|
Human   159 LATDFG-IVLLIVTRIVQGLSQSSILGGQFAIWEKWGPPQERSRLCSIALSGMLLGCFTAILIGG 222

  Fly   197 VFIDAYGWEFVFYFFGGLGVVWFAIFMFLCYSDPTSHPFIKPSEREYLV----KEIGTISRNEDL 257
            ...:..||.||||.|||:|.|...::..:.|.||.|:|:|..||:||::    :::|:..:
Human   223 FISETLGWPFVFYIFGGVGCVCCLLWFVVIYDDPVSYPWISTSEKEYIISSLKQQVGSSKQ---- 283

  Fly   258 PPTPWKAILTNLPMFALVAAQIGHDWGFYIMVTDLPKYMADVLQFSIKANGLYSSLPYVMMWIVS 322
             |.|.||:|.:||::::......|.|....||..:|.|::.|...:|:.|||.|:||:::.|::.
Human   284 -PLPIKAMLRSLPIWSICLGCFSHQWLVSTMVVYIPTYISSVYHVNIRDNGLLSALPFIVAWVIG 347

  Fly   323 VGSGFVADWMIRRGVLSTTNTRKVMTGLAAFGPAIFMVGASYAGCDRVLVVVLFTICMGLMGAYY 387
            :..|::||:::.:.....| .||:.|.|.:...:..:|...|.....:....|.|:..||.....
Human   348 MVGGYLADFLLTKKFRLIT-VRKIATILGSLPSSALIVSLPYLNSGYITATALLTLSCGLSTLCQ 411

  Fly   388 AGMKLSPLDMSPNYAGTLMAITNGIGAITGVITPYLVGVMTPNASLLEWRLVFWVAFGVLCFTAV 452
            :|:.::.||::|.|:..||..:.|..:|..||.|.:.|.:........||.||::.|.|.....:
Human   412 SGIYINVLDIAPRYSSFLMGASRGFSSIAPVIVPTVSGFLLSQDPEFGWRNVFFLLFAVNLLGLL 476

  Fly   453 IYCIWASGEVQPFNNAPIQPRSVDFEAQERKV 484
            .|.|:...:||.:             |:|||:
Human   477 FYLIFGEADVQEW-------------AKERKL 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dmGlut	NP_620115.2	2A0114euk	25..463	CDD:129972	129/441 (29%)
		MFS	77..458	CDD:119392	117/384 (30%)
SLC17A3	NP_001091956.1	2A0114euk	23..497	CDD:129972	143/487 (29%)
		MFS	98..481	CDD:119392	117/392 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148715
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6027
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D347586at33208
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.700